Drug Watch List

Note: Some of these drugs are not in trials yet or are not in trials that we are monitoring for GIST.
Note: Click on a column title to sort the list  

249 drugs found

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Targets
Xencor
SSTR2
CD3
Rapamune
Wyeth
mTOR
Torisel
Wheth Pharmaceuticals
mTOR
Topo/Target A/S
Theseus
KIT
PDGFRa
Taiho Phrmaceutical Co.
Taiho Pharmaceuticals
HSP90 subtype alpha HSP90 subtype beta
Synta
HSP90
Stanford University
CD47
Serenex
HSP90
Semafore
PI3K Class 1A
DNA-PK
mTOR
Polo-like 1 kinases
PIM1
CK2
Temodar
Schering-Plough
DNA methylation
Schering-Plough
IGF1R
Roche
MDM2
Plexxicon + Merck
Zelboraf
Plexxicon
BRAF V600E
Plexxicon
KIT
FLT3
Fms/CSF-1
CSF-1R
Piramed
PI3K Class 1
Phoenix Biotechnology, Inc.
α-3 subunit of Na-K ATPase pump
PharmaMar
Tubulin
Adriamycin + Gleevec
Pharmacia & Upjohn + Novartis
KIT
PDGFRA
Bcr-Abl
Sutent + TH-302
Pfizer, Threshold Pharmaceuticals
KIT (sunitinib)
PDGFRA (sunitinib)
VEGFRs (sunitinib)
Hypoxia (TH-302)
Sutent
Pfizer, Pfizer
KIT (sunitinib)
PDGFRA (sunitinib)
PDGFRB (sunitinib)
IGF1R (CP-751,871)
VEGFR1 (sunitinib)
VEGFR2 (sunitinib)
VEGFR3 (sunitinib)
FLT3 (sunitinib)
SCF-1R (sunitinib)
RET (sunitinib)
Sutent + Stivarga
Pfizer + Bayer
Inlyta + Keytruda
Pfizer + Merck
KIT
PDGFRa
VEGFR-1, 2, 3
T315I (BCR-ABL gatekeeper mutation)
PD-1
Sutent
Pfizer
KIT
PDGFRA
PDGFRB
VEGFR1
VEGFR2
VEGFR3
FLT3
CSF-1R
RET
Pfizer
IGF1R
Inlyta
Pfizer
VEGFR-1, 2, 3
KIT
PDGFRA
T315I (BCR-ABL gatekeeper mutation)
Pfizer
Pfizer
Campostar
Pfizer
Pfizer
Ibrance
Pfizer
Cdk4
Cdk6
Talzenna
Pfizer
PARP1
PARP2
Pfizer
PD-L1
KIT
Taxol
Pfizer
Tubulin
Peloton
HIF-2a
OSI
KIT
VEGFR
OSI
IGF1R
IR (insulin receptor)
Oncothyreon
HIF-1α
Oncothyreon
PI3K Class I
Novartis/Vernalis
Hsp90
Gleevec + PEG-Intron
Novartis, Schering
KIT
PDGFRA
Bcr-Abl
Gleevec, Sutent
Novartis, Pfizer
KIT (imatinib & sunitinib)
PDGFRA (imatinib & sunitinib)
Bcr-Abl (imatinib)
VEGFR1 (sunitinib)
VEGFR2 (sunitinib)
VEGFR3 (sunitinib)
FLT3 (sunitinib)
CSR-1R (sunitinib)
RET (sunitinib)
Gleevec + Afinitor
Novartis, Novartis
KIT
PDGFRA
Bcr-Abl
mTOR
Gleevec + Avastin
Novartis and Genentech
KIT (imatinib)
VEGFR (bevacizumab)
PDGFRA (imatinib)
PDGFRB (imatinib)
Bcr-Abl (imatinib)
Gleevec + Proleukin
Novartis + Novartis
KIT (Gleevec)
Bcr-Abl (imatinib)
PDGFRA (Gleevec)
Interleukin-2 (IL-2)
Gleevec, Tasigna
Novartis + Novartis
Both have similar targets
KIT
Bcr-abl
PDGFRA
PDGFRB
Gleevec
Novartis + Novartis
HDAC
KIT
PDGFRA
PDGFRB
Bcr-Abl
Gleevec
Novartis + Keryx
KIT
AKT
PDGFRA
Bcr-Abl
Novartis + GlaxoSmithKline
MEK 1/2
PI3K Class 1A
Gleevec + Genasense
Novartis + Genta
KIT (Gleevec)
PDGFRA (Gleevec)
Bcr-Abl (imatinib)
Bcl-2 (Genasense)
Novartis + Bristol Myers-Squibb
CTLA-4 (ipilimumab)
KIT (imatinib)
Glivec + Stivarga
Novartis + Bayer
Tasigna
Novartis
DDR-1
DDR-2
Bcr-Abl
PDGFRA
PDGFRB
KIT
MAPK11
MAPK12
ZAK
Novartis
PI3K Class I
mTOR Raptor
mTOR Rictor
Gleevec
Novartis
KIT
bcr-abl
abl
PDGFRA
PDGFRB
Novartis
HSP90
Novartis
PI3K
mTOR
Farydak
Novartis
HDAC
Afinitor/Certican
Novartis
mTOR
Sandostatin
Novartis
SSTR
Novartis
SST-1
SST-2
SST-3
SST-5
Somatostatin receptors (SST-1, SST-2, SST-3, SST-5)
Novartis
PKC alpha
KIT
PDGFRA
PDGFRA (D842V)
VEGFR1
VEGFR2
VEGFR3
FLT3
PKC beta
PKC gamma
FGFR
Novartis
IGF-1R
FAK
Novartis
PKC theta
PKC alpha
PKC beta
Novartis
VEGFR1
VEGFR2
VEGFR3
KIT
PDGFRB
Gleevec
Novartis
KIT
Bcr-Abl
PDGFRA
PKC alpha
PKC beta
PKC gamma
VEGFR
FGFR
FLT3
Novartis
PI3K Class 1
Novartis
IGF1R
Tasigna + Gleevec
Novartis
Novartis
KIT
PDGFR
VEGFR1
VEGFR2
VEGFR3
FGFR1
FGFR2
FGFR3
FLT3
RET
TrkA
CSF-1R
Novartis
PI3K Class 1A
Novartis
MEK 1/2
Novartis
PI3K Class 1A
MEK 1/2
Novartis
PI3K Class 1
mTOR Raptor
mTOR Rictor
MEK 1/2
Novartis
PI3K Class 1
MEK 1/2
Novartis
KIT (Gleevec)
PDGFRA (Gleevec)
Bcr-Abl (Gleevec)
PI3K (BKM120)
Novartis
Novartis
Novartis
FGFR
FGFR1
FGFR2
FGFR3
Novartis
KIT (imatinib)
FGFR
Gleevec + Dovitinib
Novartis
Novartis
KIT
Novartis
PD-1
Novartis
Novartis
KIT
PD-1
Ningbo Newbay
KIT
PDGFRA
Mundipharma-EDO Gmbh
Histone-deacetylase
Millennium
KIT
FLT3
PDGFRB
PDGFRA (possible)
Velcade
Millennium
26S proteasome
Velcade + Sutent
Millennium
KIT (sunitinib)
PDGFRA (sunitinib)
PDGFRB (sunitinib)
VEGFRs (sunitinib)
RET (sunitinib)
SCF-1R (sunitinib)
CSF-1R (sunitinib)
26S proteasome (bortezomib)
Millenium
KIT
FLT3
PDGFRA
Merck + Incyte
PD-1
IDO1
Zolinza + Nexavar
Merck + Bayer
KIT
PDGFRA
PDGFRB
BRAF
Mutant BRAF
CRAF
VEGFR
HDAC (vorinostat)
Zolinza
Merck
HDAC
Merck
IGF1R
Keytruda
Merck
PD-1
MedImmune LLC
IGF1
IGF2
IGF-1R (indirectly)
IR-A (indirectly)
Medimmune
PD-L1
B7H1
Loxo Oncology
TrkA
TrkB
TrkC
NTRK
Kolltan
Kit
Kirin
IGF-1R
Keryx
AKT
Yondelis
Johnson & Johnson
Rivoceranib
Jiangsu Hengrui Medicine
VEGFR2
ISA Pharmaceuticals
Insmed
IGF1R
Inhibrx, Inc.
DR5 (Death receptor 5)
Inhibrx, Inc.
DR5 (Death receptor 5)
DR5 (Death receptor 5)
Infinity
HSP90
Infinity
HSP90
Incyte
IDO1
Incyte
Intuvax
Immunicum
CD8 and CD4 positive T-cells
ImClone
IGF-1R
ImClone
IGF-1R (IMC-A12)
mTOR (CCI-779)
ImClone
PDGFRA
Ignyta
TrkA
TrkB
TrkC
ROS1
ALK
NTRK
IDRx, Inc.
KIT V654A
PDGFRa V651D

249 drugs found

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