Drug Detail

Information about PT2977

Generic Name
IND	PT2977
Brand Name (US)
Manufacturer	Peloton
Drug Type	HIF-2a inhibitor
Delivery	Oral
Approval Status
Indications
Overall Strategy	Reverse hypoxia
Strategy	Modify tumor microenvironment
Drug Category	SDH-directed

Links
	PT2977 Poster from Peloton

Trials of this drug
	A Trial of PT2977 Tablets In Patients With Advanced Solid Tumors

Trial results
	Nature Medicine May, 2021: Inhibition of hypoxia-inducible factor-2α in renal cell carcinoma with belzutifan: a phase 1 trial and biomarker analysis