Drug Watch List

Note: Some of these drugs are not in trials yet or are not in trials that we are monitoring for GIST.
Note: Click on a column title to sort the list  

255 drugs found

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Targets
OSI
KIT
VEGFR
Exelixis
KIT
VEGFR2
PDGFRB
Novartis
PI3K Class I
mTOR Raptor
mTOR Rictor
Infinity
HSP90
AB Science
KIT
PDGFR
FGFR3
Lyn
Novartis
HSP90
Novartis
PI3K
mTOR
Biogen Idec
HSP90
Amgen
VEGFR1
VEGFR2
VEGFR3
KIT
Aventis
Bristol-Myers Squibb
VEGFR2
FGFR
Synta
HSP90
Oncothyreon
HIF-1α
Novartis
SST-1
SST-2
SST-3
SST-5
Somatostatin receptors (SST-1, SST-2, SST-3, SST-5)
Oncothyreon
PI3K Class I
Millennium
KIT
FLT3
PDGFRB
PDGFRA (possible)
Piramed
PI3K Class 1
Serenex
HSP90
Exelixis
PI3K Class I
mTOR Raptor
mTOR Rictor
DNA-PK
Infinity
HSP90
Genentech/Amgen
DR4 (Death receptor 4)
DR5 (Death receptor 5)
PDK
PDKII
Novartis
PKC alpha
KIT
PDGFRA
PDGFRA (D842V)
VEGFR1
VEGFR2
VEGFR3
FLT3
PKC beta
PKC gamma
FGFR
Novartis
IGF-1R
FAK
Exelixis
PI3K Class I
Semafore
PI3K Class 1A
DNA-PK
mTOR
Polo-like 1 kinases
PIM1
CK2
Hoffmann-La Roche
IGF1R
Novartis
PKC theta
PKC alpha
PKC beta
Cobra Biomanufacturing Plc
CD8 and CD4 positive T-cells
Novartis
VEGFR1
VEGFR2
VEGFR3
KIT
PDGFRB
Keryx
AKT
Astex Therapeutics, Ltd.
HSP90
Novartis
PI3K Class 1
Novartis/Vernalis
Hsp90
Topo/Target A/S
Novartis
IGF1R
Bristol-Myers Squibb
IGF1R
Insmed
IGF1R
Exelixis
IGF1R
Scr
FGFR
Bcr-Abl
OSI
IGF1R
IR (insulin receptor)
GSK
IGF1R
Pfizer
IGF1R
ImClone
IGF-1R
Schering-Plough
IGF1R
Merck
IGF1R
Amgen
IGF1R
ChemGenex Pharmaceuticals
80S ribosome
Biogen Idec
IGF1R
Kirin
IGF-1R
MedImmune LLC
IGF1
IGF2
IGF-1R (indirectly)
IR-A (indirectly)
ARIAD
mTOR
Bristol-Myers Squibb
IGF-1R
Amgen
IGF-1R (AMG 479)
DR5 (Death receptor 5) (AMG 655)
ImClone
IGF-1R (IMC-A12)
mTOR (CCI-779)
HDAC (vorinostat)
26S proteasome (bortezomib)
Bayer/ACT BIOTECH
KIT
VEGFR2
VEGFR3
PDGFRB
Biogen Idec
HSP90
Millenium
KIT
FLT3
PDGFRA
Genentech/Piramed Ltd.
PI3K
mTOR
Plexxicon
KIT
FLT3
Fms/CSF-1
CSF-1R
Phoenix Biotechnology, Inc.
α-3 subunit of Na-K ATPase pump
Genentech/Exelixis
MEK
Genentech
PI3K
MEK
EntreMed
Aurora Kinase A
Aurora Kinase B
VEGFR2
KIT
FGFR1
Arog Pharmaceuticals
PDGFRA
PDGFRB
PDGFRA (D842V)
FLT3
AVEO Pharmaceuticals, Inc.
VEGFR-1, 2, 3
KIT
PDGFRB
Novartis
KIT
PDGFR
VEGFR1
VEGFR2
VEGFR3
FGFR1
FGFR2
FGFR3
FLT3
RET
TrkA
CSF-1R
Array Biopharma/AstraZeneca
MEK 1/2
MEK 1/2
mTOR (CCI-779)
ImClone
PDGFRA
Roche
MDM2
Novartis
PI3K Class 1A
Novartis
MEK 1/2
Novartis
PI3K Class 1A
MEK 1/2
Novartis
PI3K Class 1
mTOR Raptor
mTOR Rictor
MEK 1/2
Novartis
PI3K Class 1
MEK 1/2
Hoffman-La Roche
gama-secretase
Novartis
KIT (Gleevec)
PDGFRA (Gleevec)
Bcr-Abl (Gleevec)
PI3K (BKM120)
Novartis + Bristol Myers-Squibb
CTLA-4 (ipilimumab)
KIT (imatinib)
Novartis + GlaxoSmithKline
MEK 1/2
PI3K Class 1A
GlaxoSmithKline
KIT (pazopanib)
MEK (Trametinib)
VEGFRS (pazopanib)
PDGFRA (pazopanib)
Pfizer
Pfizer
Pfizer
EMD Serono
EMD Serono
EMD Serono
Genentech
Genentech
Bayer
PI3K
Bayer
MEK
Bayer
PI3K
MEK
Novartis
Novartis
Bristol-Myers Squibb
LAG-3
Bristol-Myers Squibb
GlaxoSmithKline
Incyte
IDO1
Cornerstone Pharmaceuticals
α-ketoglutarate dehydrogenase (KGDH)
Pyruvate dehydrogenase (PDH)
Novartis
FGFR
FGFR1
FGFR2
FGFR3
VEGFR2
Novartis
KIT (imatinib)
FGFR
Calithera Biosciences, Inc
Glutaminase (GLS)
Boston Biomedical
NANOG
Novartis
KIT
Genentech
IDO1
Cogent Biosciences
KIT
Cogent Biosciences
KIT
FLT3
CSF-1R
Hoffman-La Roche
PD-L1
Hoffman-La Roche
Plexxicon + Merck
Novartis
PD-1
ISA Pharmaceuticals
Novartis

255 drugs found

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