Types of GIST Trials

What type of trial are you looking for?

Each clinical trial is designed to study and analyze new interventions for a specific disease or condition. Therefore, each clinical trial is classified into different trial phases and categories. In this data base, GIST clinical trials are divided into three categories: First line, Resistant, and Preventative (Adjuvant). The table below shows the definition of each category and the link to the list of currently recruiting trials. Additionally, GIST clinical trials can also be found by their specific mutational subset, such as D842V and SDH-Deficient.

Search for Clinical Trials

Clinical Trial Type	Clinical Trial Description
First-line Trials	Trials for patients who never had Gleevec (imatinib) before and have metastatic or unresectable disease.
Drug-resistant GIST	Trials for patients who have had resistantance to Gleevec (imatinib), Sutent (sunitinib), Stivarga (regorafenib).
Preventative (Adjuvant)Treatment Trials	Trials of Gleevec (imatinib) to try to prevent a recurrence after surgical removal of a primary tumor.
All Trials	Includes trials that are no longer open
"Recruiting" Trials	Shows all recruiting trials including; First-line, Gleevec/Sutent-resistant and Adjuvant trials
Search Trials	This page allows for custom searches. For example, you can search for all drugs of a certain class like all HSP90 inhibitors or all PI3K inhibitors. This is especially helpful if you are searching for a class of drug and something near your home.
Clinical Trial Site List	Returns a list of all of the clinical trial sites that have a trial that we are tracking. This is very helpful if you are interested in a particular site and want to see what trials are available at that site. The site list is sortable by site, city, state and country.
Search Drugs	Provides for a search of drugs by drug name, drug category, approval status or drug target. Returns a list of the drugs that we are tracking including all of the ones listed in the trials and a few others of interest. From the list you can select any drug for more detailed information about the drug. For approved drugs this typically includes links to prescribing information, patient assistance programs, trial results and more.

Clinical Trial Type

Clinical Trial Description

First-line Trials

Trials for patients who never had Gleevec (imatinib) before and have metastatic or unresectable disease.

Drug-resistant GIST

Trials for patients who have had resistantance to Gleevec (imatinib), Sutent (sunitinib), Stivarga (regorafenib).

Preventative (Adjuvant)Treatment Trials

Trials of Gleevec (imatinib) to try to prevent a recurrence after surgical removal of a primary tumor.

All Trials

Includes trials that are no longer open

"Recruiting" Trials

Shows all recruiting trials including; First-line, Gleevec/Sutent-resistant and Adjuvant trials

Search Trials

This page allows for custom searches. For example, you can search for all drugs of a certain class like all HSP90 inhibitors or all PI3K inhibitors. This is especially helpful if you are searching for a class of drug and something near your home.

Clinical Trial Site List

Returns a list of all of the clinical trial sites that have a trial that we are tracking. This is very helpful if you are interested in a particular site and want to see what trials are available at that site. The site list is sortable by site, city, state and country.

Search Drugs

Provides for a search of drugs by drug name, drug category, approval status or drug target. Returns a list of the drugs that we are tracking including all of the ones listed in the trials and a few others of interest. From the list you can select any drug for more detailed information about the drug. For approved drugs this typically includes links to prescribing information, patient assistance programs, trial results and more.