Drug Detail

Information about INBRX-109 + Temozolomide

Generic Name
IND	INBRX-109 + Temozolomide
Brand Name (US)
Manufacturer	Inhibrx, Inc.
Drug Type	DR5 Agonist Plus Alkylating agent
Delivery	Intravenous and Oral
Approval Status
Indications
Overall Strategy	GIST cell based
Strategy	Damage DNA and activate cell death receptor
Drug Category	SDH-directed

Alkylating agents damage DNA and trigger cell death.. DR5 agonists promote tumor cell death by activating the tumor cell death mechanism.