Drug Watch List

Note: Some of these drugs are not in trials yet or are not in trials that we are monitoring for GIST.
Note: Click on a column title to sort the list  

255 drugs found

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Targets
None, Adriamycin
Aventis,
Gemzar, Taxotere
Cobra Biomanufacturing Plc
CD8 and CD4 positive T-cells
Temodar
Schering-Plough
DNA methylation
Tasigna + Gleevec
Novartis
Votrient + Zolinza
GlaxoSmithKline & Merck
KIT (pazopanib)
PDGFRA (pazopanib)
PDGFRB (pazopanib)
VEGFRS (pazopanib)
HDAC (vorinostat)
Votrient + Hycamtin
GlaxoSmithKline
KIT (pazopanib)
PDGFRA (pazopanib)
PDGFRB (pazopanib)
VEGFRS (pazopanib)
Topoisomerase I (topetecan)
GlaxoSmithKline
KIT (pazopanib)
MEK (Trametinib)
VEGFRS (pazopanib)
PDGFRA (pazopanib)
Novartis
GlaxoSmithKline
Gleevec + Dovitinib
Novartis
Hoffman-La Roche
Glivec + Stivarga
Novartis + Bayer
Plexxicon + Merck
Opdivo + Yervoy
Bristol-Myers Squibb
PD-1
CTLA-4
Tafinlar + Mekinist
GlaxoSmithKline
BRAF V600E
BRAF V600K
MEK 1/2
Inlyta + Keytruda
Pfizer + Merck
KIT
PDGFRa
VEGFR-1, 2, 3
T315I (BCR-ABL gatekeeper mutation)
PD-1
Intuvax
Immunicum
CD8 and CD4 positive T-cells
Tumor antigens
BCL-2
KIT
Raf-1
PDGFRB
BRAF
mutant BRAF
FLT3
VEGFR
MEK1/2
KIT
FLT3
Fms/CSF-1
CSF-1R
PD-L1
CTLA-4
Merck + Incyte
PD-1
IDO1
BRAFTOVI
Array Biopharma
BRAF V600E
BRAF V600K
Venclexta
Abbvie / Genetech
BCL-2
CStone Pharmaceuticals
PDL-1
KIT
PDGFRa
Pfizer
PD-L1
KIT
KIT
PDGFRa
XPO1
Taxol
Pfizer
Tubulin
Novartis
KIT
PD-1
Bayer, Merck
KIT
PD-L1
Stivarga
Bayer
MEK
Deciphera / Array
Taiho Phrmaceutical Co.
KIT
PDGFRa
PD-L1
Novartis
FGFR
FGFR1
FGFR2
FFGFR3
KIT
PDGFRA
VEGFR2
KIT
PDGFRA
Menin-MLL
Advanced Accelerator Applications
Advanced Accelerator Aplications
GRPR
AB Science
KIT
PDGFR
FGFR3
Lyn
Abbott
BCL-2
Novartis
PKC theta
PKC alpha
PKC beta
Inlyta
Pfizer
VEGFR-1, 2, 3
KIT
PDGFRA
T315I (BCR-ABL gatekeeper mutation)
Advenchen Laboratories
KIT
PDGFRa
VEGFR2
VEGFR3
Amgen
IGF1R
Amgen
IGF-1R (AMG 479)
DR5 (Death receptor 5) (AMG 655)
Amgen
KRAS G12C
Amgen
VEGFR1
VEGFR2
VEGFR3
KIT
Tasigna
Novartis
DDR-1
DDR-2
Bcr-Abl
PDGFRA
PDGFRB
KIT
MAPK11
MAPK12
ZAK
ARIAD
mTOR
Iclusig
ARIAD
Bcr-Abl
KIT
PDGFRA
VEGFR
FLT3
FGFR
EPH
SRC family
RET
TIE-2
ArQule
AKT
Astex Therapeutics, Ltd.
HSP90
Novartis
HSP90
AVEO Pharmaceuticals, Inc.
VEGFR-1, 2, 3
KIT
PDGFRB
Recentin
AstraZeneca
VEGFR1
VEGFR2
VEGFR3
KIT
PDGFRA
PDGFRB
Array Biopharma/AstraZeneca
MEK 1/2
MEK 1/2
mTOR (CCI-779)
Bayer
FGFR1
FGFR2
FGFR3
FGFR4
Nexavar
Bayer
KIT
Raf-1
PDGFRB
BRAF
Mutant BRAF
FLT3
VEGFR
Nexavar + Avastin
Bayer and Genentech
KIT (Sorafenib)
PDGFR (Sorafenib)
VEGFR (Sorafenib)
VEGFR (Bevacizumab)
BRAF (Sorafenib)
mutant BRAF (Sorafenib)
CRAF
Bayer/ACT BIOTECH
KIT
VEGFR2
VEGFR3
PDGFRB
Stivarga
Bayer
Raf-1
BRAF
VEGRF2
VEGFR3
KIT
PDGFRA
PDGFRB
RET
TIE-2
DDR-2
FGFR1
FGFR2
Trk2A
Eph2A
BRAF V600E
SAPK2
PTK5
Abl
Bayer
PI3K
Bayer
PI3K
MEK
Bayer
MEK
Boston Biomedical
NANOG
Avastin
Genentech Bio-oncology
VEGF-A
Novartis
PI3K Class I
mTOR Raptor
mTOR Rictor
Novartis
PI3K Class 1
mTOR Raptor
mTOR Rictor
MEK 1/2
BerGenBio
AXL
Novartis
FGFR
FGFR1
FGFR2
FGFR3
VEGFR2
Novartis
PI3K
mTOR
Biogen Idec
IGF1R
Biogen Idec
HSP90
Biogen Idec
HSP90
Novartis
PI3K Class 1
Novartis + GlaxoSmithKline
MEK 1/2
PI3K Class 1A
Novartis
PI3K Class 1
MEK 1/2
AYVAKIT
Blueprint Medicines
PDGFRA (D842V)
KIT exon 17
KIT D816V
Talzenna
Pfizer
PARP1
PARP2
Bristol-Myers Squibb
IGF1R
Sprycel
Bristol-Myers Squibb
KIT
bcr-abl
SRC family
PDGFRB
EPHA2
LCK
YES
FYN
SRC
Bristol-Myers Squibb
VEGFR2
FGFR
Bristol-Myers Squibb
IGF-1R
Opdivo
Bristol-Myers Squibb
PD-1
Bristol-Myers Squibb
Bristol-Myers Squibb
LAG-3
Velcade + Sutent
Millennium
KIT (sunitinib)
PDGFRA (sunitinib)
PDGFRB (sunitinib)
VEGFRs (sunitinib)
RET (sunitinib)
SCF-1R (sunitinib)
CSF-1R (sunitinib)
26S proteasome (bortezomib)
Novartis
PI3K Class 1A
Calithera & Pfizer
Glutaminase (GLS)
PARP1
PARP2
Calithera Biosciences, Inc
Glutaminase (GLS)
Torisel
Wheth Pharmaceuticals
mTOR
Cogent Biosciences
KIT
Cogent Bioscience
KIT
Cogent Biosciences
KIT Exon 17
ChemGenex Pharmaceuticals
80S ribosome
Pfizer
IGF1R
Arog Pharmaceuticals
PDGFRA
PDGFRB
PDGFRA (D842V)
FLT3
AstraZeneca
CTLA-4
Cornerstone Pharmaceuticals
α-ketoglutarate dehydrogenase (KGDH)
Pyruvate dehydrogenase (PDH)
Gleevec, Sutent
Daiichi Sankyo
DR5 (TRAIL-R2) (CS-1008)
KIT (imatinib & sunitinib)
PDGFRA (imatinib & sunitinib)
Bcr-abl
VEGFRs (sunitinib)
FLT3 (sunitinib)
CSF-1R (sunitinib)
RET (sunitinib)
CStone Pharmaceuticals
PD-L1
Ayvakit
Blueprint Medicines Corporation
PDGFRA (D842V)
KIT exon 17
KIT D816V
Sprycel + Avastin
Bristol Myers-Squibb + Genetech
KIT
BCR-ABL
PDGFRB
SRC family
EPHA2
VEGFA (Bevacizumab)
PDK
PDKII
QINLOCK
Deciphera Pharmaceuticals, LLC
KIT
PDGFRA
VEGFR2
TIE-2
Fms/CSF-1
BRAF
PDGFRB
Deciphera
Deciphera
ULK1/2
Deciphera
ULK1/2
KIT
Liporaxel
Dae Hwa Pharmaceutical
Tubulin
Adriamycin + Gleevec
Pharmacia & Upjohn + Novartis
KIT
PDGFRA
Bcr-Abl
Daichi Sanyo
TOPO-1
GPR20
Lenvima
Eisai Co.
KIT
PDGFRa
VEGFR1
VEGFR2
VEGFR3
RET
FGFR1
FGFR2
FGFR3
FGFR4

255 drugs found

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