Drug Detail

Information about LOP628

Generic Name
IND	LOP628
Brand Name (US)
Manufacturer	Novartis
Drug Type
Delivery	Intravenous
Approval Status
Indications
Overall Strategy	KIT Protein Based
Strategy	Block KIT
Drug Category	c-KIT Antibody

LOP628 is an antibody-drug conjugate (ADC) consisting of an anti-cKit humanized IgG1/κ antibody conjugated to a maytansine payload via a non-cleavable linker.

LOP628 provides an opportunity to target cKit overexpressing tumors.