Drug Detail

Information about Tinostamustine

Generic Name	Tinostamustine
IND	EDO-S101
Brand Name (US)
Manufacturer	Mundipharma-EDO Gmbh
Drug Type	Alkylating histone-deacetylase inhibitor
Delivery	Intravenous
Approval Status	Phase 2
Indications
Overall Strategy	Reverse hypermethylation
Strategy	Unblock cell death genes
Drug Category	HDAC inhibitor

An alkylating histone-deacetylase inhibitor (HDACi) fusion molecule composed of the alkylating agent bendamustine fused to the pan-HDACi vorinostat, with potential bi-functional antineoplastic activity.