Generic Name |
Imatinib + Peginterferon alfa-2b | |
---|---|---|
IND |
Imatinib + Pegylated Interferon-a 2B | |
Brand Name (US) |
Gleevec + PEG-Intron | |
Manufacturer |
Novartis, Schering | |
Drug Type |
||
Delivery |
Oral Subcutaneous | |
Approval Status |
Both are approved. This combination is not approved for GIST. It was evaluated in a phase 2 trial for GIST. | |
Indications |
||
Overall Strategy |
GIST cell based KIT Protein Based | |
Strategy |
Stimulate the immune system | |
Drug Category |
KIT/PDGFRA inhibitor Immune stimulate |
PEG-Intron is a long acting interferon. Interferons are proteins released in the body in response to viral infections. Interferons are important for fighting viruses in the body, for regulating reproduction of cells, and for regulating the immune system.
PEG-Intron is a specific interferon used to treat chronic hepatitis C.