Drug Detail

Information about Gleevec, Sutent

Generic Name	Imatinib + Sunitinib
IND	STI571 + SU11248
Brand Name (US)	Gleevec, Sutent
Manufacturer	Novartis, Pfizer
Drug Type	Tyrosine Kinase Inhibitor
Delivery	Oral
Approval Status	Both are approved for GIST however, this combination is not approved for GIST. It is being evaluated in a phase 1 trial for GIST.
Indications
Overall Strategy	KIT Protein Based
Strategy	Block KIT
Drug Category	KIT/PDGFRA inhibitor

Imatinib and sunitinib are the two currently approved therapies for GIST. The combination is being tested in a phase I trial.