Drug Detail

Information about Gleevec, Sutent

Generic Name
Imatinib + Sunitinib
IND
STI571 + SU11248
Brand Name (US)
Gleevec, Sutent
Manufacturer
Novartis, Pfizer
Drug Type
Tyrosine Kinase Inhibitor
Delivery
Oral
Approval Status
Both are approved for GIST however, this combination is not approved for GIST. It is being evaluated in a phase 1 trial for GIST.
Indications
Overall Strategy
KIT Protein Based
Strategy
Block KIT
Drug Category
KIT/PDGFRA inhibitor

Imatinib and sunitinib are the two currently approved therapies for GIST. The combination is being tested in a phase I trial.


Links


Trials of this drug

  

Imatinib Mesylate and Sunitinib in Treating Patients With Gastrointestinal Stromal Tumors
   

Trial results


Search for this drug/combination in:

ClinicalTrials.gov

ASCO

Pubmed