Generic Name |
||
---|---|---|
IND |
INBRX-109 | |
Brand Name (US) |
||
Manufacturer |
Inhibrx, Inc. | |
Drug Type |
DR5 agonist | |
Delivery |
Intravenous | |
Approval Status |
Phase 2 | |
Indications |
||
Overall Strategy |
GIST cell based | |
Strategy |
Activate Death Receptor | |
Drug Category |
SDH-directed |
The FDA has granted an orphan drug designation to INBRX-109 for the treatment of chondrosarcoma, according to a press release by Inhibrx, Inc.1
INBRX-109 is a tetravalent death receptor 5 (DR5) agonist antibody that is meant to leverage tumor-biased cell death caused by DR5 activation.and avoid apoptosis of normal cells.