Drug Detail

Information about Plocabulin

Generic Name	Plocabulin
IND	PM060184
Brand Name (US)
Manufacturer	PharmaMar
Drug Type
Delivery	Intraveneous
Approval Status	Phase 1
Indications
Overall Strategy	Modulate microtubule dynamics
Strategy	Tubulin binding agent
Drug Category	Tubulin inhibitor

PM184
This compound inhibits tubulin polymerization. These proteins form part of the cell’s skeleton (the cytoskeleton). As a result, the cytoskeleton becomes degraded and the tumor cells lose the capacity to mobilize and divide.