Drug Watch List

Note: Some of these drugs are not in trials yet or are not in trials that we are monitoring for GIST.
Note: Click on a column title to sort the list  

255 drugs found

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Targets
OSI
KIT
VEGFR
Exelixis
KIT
VEGFR2
PDGFRB
Novartis
PI3K Class I
mTOR Raptor
mTOR Rictor
Infinity
HSP90
Novartis
HSP90
Novartis
PI3K
mTOR
Oncothyreon
HIF-1α
Oncothyreon
PI3K Class I
Serenex
HSP90
Exelixis
PI3K Class I
mTOR Raptor
mTOR Rictor
DNA-PK
Genentech/Amgen
DR4 (Death receptor 4)
DR5 (Death receptor 5)
Exelixis
PI3K Class I
Semafore
PI3K Class 1A
DNA-PK
mTOR
Polo-like 1 kinases
PIM1
CK2
Hoffmann-La Roche
IGF1R
Novartis
PI3K Class 1
Novartis/Vernalis
Hsp90
Novartis
IGF1R
Bristol-Myers Squibb
IGF1R
Insmed
IGF1R
Exelixis
IGF1R
Scr
FGFR
Bcr-Abl
GSK
IGF1R
Schering-Plough
IGF1R
Merck
IGF1R
Amgen
IGF1R
Biogen Idec
IGF1R
Kirin
IGF-1R
MedImmune LLC
IGF1
IGF2
IGF-1R (indirectly)
IR-A (indirectly)
Bristol-Myers Squibb
IGF-1R
Amgen
IGF-1R (AMG 479)
DR5 (Death receptor 5) (AMG 655)
HDAC (vorinostat)
26S proteasome (bortezomib)
Biogen Idec
HSP90
Genentech/Piramed Ltd.
PI3K
mTOR
Genentech
PI3K
MEK
EntreMed
Aurora Kinase A
Aurora Kinase B
VEGFR2
KIT
FGFR1
MEK 1/2
mTOR (CCI-779)
Roche
MDM2
Novartis
PI3K Class 1A
Novartis
PI3K Class 1A
MEK 1/2
Novartis
PI3K Class 1
mTOR Raptor
mTOR Rictor
MEK 1/2
Novartis
PI3K Class 1
MEK 1/2
Hoffman-La Roche
gama-secretase
Novartis
KIT (Gleevec)
PDGFRA (Gleevec)
Bcr-Abl (Gleevec)
PI3K (BKM120)
Novartis + GlaxoSmithKline
MEK 1/2
PI3K Class 1A
Pfizer
Pfizer
Pfizer
EMD Serono
EMD Serono
Genentech
Genentech
Bayer
PI3K
Bayer
MEK
Bayer
PI3K
MEK
Novartis
Bristol-Myers Squibb
LAG-3
Incyte
IDO1
Cornerstone Pharmaceuticals
α-ketoglutarate dehydrogenase (KGDH)
Pyruvate dehydrogenase (PDH)
Novartis
KIT (imatinib)
FGFR
Boston Biomedical
NANOG
Novartis
KIT
Genentech
IDO1
Cogent Biosciences
KIT
Novartis
PD-1
ISA Pharmaceuticals
Novartis
Stanford University
CD47
Kolltan
Kit
ArQule
AKT
BerGenBio
AXL
Xencor
SSTR2
CD3
Peloton
HIF-2a
Amgen
KRAS G12C
Taiho Pharmaceuticals
HSP90 subtype alpha HSP90 subtype beta
CStone Pharmaceuticals
PD-L1
CStone Pharmaceuticals
PDL-1
KIT
PDGFRa
Daichi Sanyo
TOPO-1
GPR20
Ningbo Newbay
KIT
PDGFRA
Theseus
KIT
PDGFRa
IDRx, Inc.
KIT V654A
PDGFRa V651D
Advanced Accelerator Applications
Inhibrx, Inc.
DR5 (Death receptor 5)
Inhibrx, Inc.
DR5 (Death receptor 5)
DR5 (Death receptor 5)
Deciphera
ULK1/2
Deciphera
Advenchen Laboratories
KIT
PDGFRa
VEGFR2
VEGFR3
Rivoceranib
Jiangsu Hengrui Medicine
VEGFR2
Hoffman-La Roche
PD-L1
AYVAKIT
Blueprint Medicines
PDGFRA (D842V)
KIT exon 17
KIT D816V
Ayvakit
Blueprint Medicines Corporation
PDGFRA (D842V)
KIT exon 17
KIT D816V
Pfizer
PD-L1
KIT
Inlyta
Pfizer
VEGFR-1, 2, 3
KIT
PDGFRA
T315I (BCR-ABL gatekeeper mutation)
Inlyta + Keytruda
Pfizer + Merck
KIT
PDGFRa
VEGFR-1, 2, 3
T315I (BCR-ABL gatekeeper mutation)
PD-1
Topo/Target A/S
HIF2A
Merck
ATR
Avastin
Genentech Bio-oncology
VEGF-A
Cogent Bioscience
KIT
Cogent Biosciences
KIT Exon 17
Novartis
MEK 1/2
MEK1/2
KIT
FLT3
Fms/CSF-1
CSF-1R
Velcade
Millennium
26S proteasome
Velcade + Sutent
Millennium
KIT (sunitinib)
PDGFRA (sunitinib)
PDGFRB (sunitinib)
VEGFRs (sunitinib)
RET (sunitinib)
SCF-1R (sunitinib)
CSF-1R (sunitinib)
26S proteasome (bortezomib)
Bristol-Myers Squibb
VEGFR2
FGFR
Cometriq
Exelixis
c-MET
VEGFR-1, 2, 3
RET
KIT
FLT3
TEK
AXL
TRKB
TIE-2
Recentin
AstraZeneca
VEGFR1
VEGFR2
VEGFR3
KIT
PDGFRA
PDGFRB
ImClone
IGF-1R
ImClone
IGF-1R (IMC-A12)
mTOR (CCI-779)
Biogen Idec
HSP90
Genentech/Exelixis
MEK
Hoffman-La Roche
Arog Pharmaceuticals
PDGFRA
PDGFRB
PDGFRA (D842V)
FLT3
Gleevec, Sutent
Daiichi Sankyo
DR5 (TRAIL-R2) (CS-1008)
KIT (imatinib & sunitinib)
PDGFRA (imatinib & sunitinib)
Bcr-abl
VEGFRs (sunitinib)
FLT3 (sunitinib)
CSF-1R (sunitinib)
RET (sunitinib)
Tafinlar + Mekinist
GlaxoSmithKline
BRAF V600E
BRAF V600K
MEK 1/2
TAFINLAR
GlaxoSmithKline
BRAF
BRAF V600E
BRAF V600K
Sprycel
Bristol-Myers Squibb
KIT
bcr-abl
SRC family
PDGFRB
EPHA2
LCK
YES
FYN
SRC

255 drugs found

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