Generic Name |
Imatinib + Ipilimumab | |
---|---|---|
IND |
Imatinib + Ipilimumab | |
Brand Name (US) |
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Manufacturer |
Novartis + Bristol Myers-Squibb | |
Drug Type |
Tyrosine Kinase Inhibitor and Monoclonal antibody | |
Delivery |
Oral + Intravenous | |
Approval Status |
Both are approved. This combination is not approved for GIST. It is being evaluated in a phase 1 trial for GIST. | |
Indications |
||
Overall Strategy |
KIT Protein and immune system | |
Strategy |
Block KIT + Stimulate the immune system | |
Drug Category |
KIT/PDGFRA inhibitor + CTLA4 inhibitor |
Links |
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Trials of this drug |
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|
Ipilimumab and Imatinib Mesylate in Advanced Cancer |
Trial results |