Drug Detail

Information about Olaratumab

Generic Name	Olaratumab
IND	IMC-3G3
Brand Name (US)
Manufacturer	ImClone
Drug Type	monoclonal antibody
Delivery	Intravenous
Approval Status	Phase 2
Indications
Overall Strategy	KIT Protein Based
Strategy	Block PDGFRA
Drug Category	PDGFRa inhibitor

IMC-3G3, a fully human monoclonal antibody of the immunoglobulin G subclass 1, specifically binds to the human PDGF receptor alpha (PDGFRalpha) with high affinity and blocks PDGF ligand binding and PDGFRalpha activation

ImClone was acquired by Eli Lilly in 2008.