Drug Detail

Information about Tivozanib

Generic Name	Tivozanib
IND	AV-951, KRN-951
Brand Name (US)
Manufacturer	AVEO Pharmaceuticals, Inc.
Drug Type	Tyrosine Kinase Inhibitor
Delivery	Oral
Approval Status	Phase 3
Indications	Renal cell carcinoma (RCC) in US
Overall Strategy	KIT Protein Based
Strategy	Block KIT
Drug Category	KIT/PDGFRA inhibitor+ VEGF inhibitor (TKI)

AV-951 is an extremely potent inhibitor of the VEGF receptors and KIT. It is being developed for kidney cancer and there are no clinical trials for GIST at this time.