Drug Detail

Information about Ridaforolimus

Generic Name	Ridaforolimus
IND	AP23573 (MK-8669)
Brand Name (US)
Manufacturer	ARIAD
Drug Type	mTOR inhibitor
Delivery	Intravenous
Approval Status	Phase 3
Indications
Overall Strategy	GIST cell based
Strategy	Block related tumor signal paths
Drug Category	mTOR inhibitor

MK-8669 is an mTOR inhibitor manufactured by ARIAD. It was formerly known as deforolimus. ARIAD is collaborating with Merck & Co. (Merck) to develop and commercialize AP23573.
Blocking mTOR creates a starvation-like effect in cancer cells by interfering with cell growth, division, metabolism and angiogenesis.