Drug Watch List

Note: Some of these drugs are not in trials yet or are not in trials that we are monitoring for GIST.
Note: Click on a column title to sort the list  

249 drugs found

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Targets
Schering-Plough
IGF1R
Merck
IGF1R
Amgen
IGF1R
ChemGenex Pharmaceuticals
80S ribosome
Biogen Idec
IGF1R
Kirin
IGF-1R
MedImmune LLC
IGF1
IGF2
IGF-1R (indirectly)
IR-A (indirectly)
ARIAD
mTOR
Bristol-Myers Squibb
IGF-1R
Amgen
IGF-1R (AMG 479)
DR5 (Death receptor 5) (AMG 655)
ImClone
IGF-1R (IMC-A12)
mTOR (CCI-779)
HDAC (vorinostat)
26S proteasome (bortezomib)
Bayer/ACT BIOTECH
KIT
VEGFR2
VEGFR3
PDGFRB
Biogen Idec
HSP90
Millenium
KIT
FLT3
PDGFRA
Genentech/Piramed Ltd.
PI3K
mTOR
Plexxicon
KIT
FLT3
Fms/CSF-1
CSF-1R
Phoenix Biotechnology, Inc.
α-3 subunit of Na-K ATPase pump
Genentech/Exelixis
MEK
Genentech
PI3K
MEK
EntreMed
Aurora Kinase A
Aurora Kinase B
VEGFR2
KIT
FGFR1
Arog Pharmaceuticals
PDGFRA
PDGFRB
PDGFRA (D842V)
FLT3
AVEO Pharmaceuticals, Inc.
VEGFR-1, 2, 3
KIT
PDGFRB
Novartis
KIT
PDGFR
VEGFR1
VEGFR2
VEGFR3
FGFR1
FGFR2
FGFR3
FLT3
RET
TrkA
CSF-1R
Array Biopharma/AstraZeneca
MEK 1/2
MEK 1/2
mTOR (CCI-779)
ImClone
PDGFRA
Roche
MDM2
Novartis
PI3K Class 1A
Novartis
MEK 1/2
Novartis
PI3K Class 1A
MEK 1/2
Novartis
PI3K Class 1
mTOR Raptor
mTOR Rictor
MEK 1/2
Novartis
PI3K Class 1
MEK 1/2
Hoffman-La Roche
gama-secretase
Novartis
KIT (Gleevec)
PDGFRA (Gleevec)
Bcr-Abl (Gleevec)
PI3K (BKM120)
Novartis + Bristol Myers-Squibb
CTLA-4 (ipilimumab)
KIT (imatinib)
Novartis + GlaxoSmithKline
MEK 1/2
PI3K Class 1A
GlaxoSmithKline
KIT (pazopanib)
MEK (Trametinib)
VEGFRS (pazopanib)
PDGFRA (pazopanib)
Pfizer
Pfizer
Pfizer
EMD Serono
EMD Serono
EMD Serono
Genentech
Genentech
Bayer
PI3K
Bayer
MEK
Bayer
PI3K
MEK
Novartis
Novartis
Bristol-Myers Squibb
LAG-3
Bristol-Myers Squibb
GlaxoSmithKline
Incyte
IDO1
Cornerstone Pharmaceuticals
α-ketoglutarate dehydrogenase (KGDH)
Pyruvate dehydrogenase (PDH)
Novartis
FGFR
FGFR1
FGFR2
FGFR3
Novartis
KIT (imatinib)
FGFR
Calithera Biosciences, Inc
Glutaminase (GLS)
Boston Biomedical
NANOG
Novartis
KIT
Genentech
IDO1
Cogent Biosciences
KIT
Cogent Biosciences
KIT
FLT3
CSF-1R
Hoffman-La Roche
PD-L1
Hoffman-La Roche
Plexxicon + Merck
Novartis
PD-1
ISA Pharmaceuticals
Novartis
Medimmune
PD-L1
B7H1
Stanford University
CD47
Kolltan
Kit
Tumor antigens
ArQule
AKT
Ignyta
TrkA
TrkB
TrkC
ROS1
ALK
NTRK
Loxo Oncology
TrkA
TrkB
TrkC
NTRK
Abbott
BCL-2
BCL-2
KIT
Raf-1
PDGFRB
BRAF
mutant BRAF
FLT3
VEGFR
BerGenBio
AXL
Advanced Accelerator Aplications
GRPR
Astex Pharmaceuticals
MEK1/2
KIT
FLT3
Fms/CSF-1
CSF-1R
AstraZeneca
CTLA-4
PD-L1
CTLA-4
Merck + Incyte
PD-1
IDO1
Incyte
Mundipharma-EDO Gmbh
Histone-deacetylase
Xencor
SSTR2
CD3
PharmaMar
Tubulin
Edo
Peloton
HIF-2a
Calithera & Pfizer
Glutaminase (GLS)
PARP1
PARP2
Amgen
KRAS G12C
Taiho Pharmaceuticals
HSP90 subtype alpha HSP90 subtype beta
CStone Pharmaceuticals
PD-L1
CStone Pharmaceuticals
PDL-1
KIT
PDGFRa
Pfizer
PD-L1
KIT
KIT
PDGFRa
XPO1
Advenchen Laboratories
KIT
PDGFRa
VEGFR2
VEGFR3
Novartis
KIT
PD-1
Ascentage Pharma
Bcr-Abl
KIT
Bayer, Merck
KIT
PD-L1
Daichi Sanyo
TOPO-1
GPR20
Bayer
FGFR1
FGFR2
FGFR3
FGFR4
Ningbo Newbay
KIT
PDGFRA
cKit
PDGFRa
VEGFR2
VEGFR3
FLT1
FLT3
Deciphera / Array
Theseus
KIT
PDGFRa
Cogent Bioscience
KIT
Cogent Biosciences
KIT Exon 17
IDRx, Inc.
KIT V654A
PDGFRa V651D

249 drugs found

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