Drug Detail

Information about Tinostamustine

Generic Name
Tinostamustine
IND
EDO-S101
Brand Name (US)
Manufacturer
Drug Type
Alkylating histone-deacetylase inhibitor
Delivery
Approval Status
Phase 2
Indications
Overall Strategy
GIST Tumor Based
Strategy
Interfere with production of new DNA
Drug Category

Tinostamustine (EDO-S101) is a new chemical entity, an AK-DAC (a first-in-class alkylating deacetylase inhibiting molecule) that, in preclinical studies, has been shown to simultaneously improve access to the DNA strands within cancer cells, break them and block damage repair. This Phase 1/2 study will enroll patients with various advanced solid tumors.


Links


Trials of this drug


Trial results


Search for this drug/combination in:

ClinicalTrials.gov

ASCO

Pubmed