Generic Name |
Dabrafenib + | |
---|---|---|
IND |
||
Brand Name (US) |
Tafinlar + Mekinist | |
Manufacturer |
GlaxoSmithKline | |
Drug Type |
Kinase inhibitor | |
Delivery |
Oral | |
Approval Status |
Approved for a non-GIST cancer | |
Indications |
Melanoma with BRAF mutations | |
Overall Strategy |
Oncogenic Signal Path Based | |
Strategy |
Block BRAF | |
Drug Category |
BRAF Inhibitor + MEK Inhibitor |
For GIST with BRAF mutation.
Links |
|
Trials of this drug |
|
|
Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers |
Trial results |