Drug Watch List

Note: Some of these drugs are not in trials yet or are not in trials that we are monitoring for GIST.
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255 drugs found

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Targets
GSK
IGF1R
Genentech/Piramed Ltd.
PI3K
mTOR
Genentech
Genentech/Exelixis
MEK
Genentech
PI3K
MEK
Piramed
PI3K Class 1
Erivedge
Genentech
SMO (smoothened receptor)
Genentech
Istodax
Gloucester Pharmaceuticals
HDAC
Yondelis
Johnson & Johnson
EntreMed
Aurora Kinase A
Aurora Kinase B
VEGFR2
KIT
FGFR1
Mundipharma-EDO Gmbh
Histone-deacetylase
Edo
Lenvima
Eisai Co.
KIT
PDGFRa
VEGFR1
VEGFR2
VEGFR3
RET
FGFR1
FGFR2
FGFR3
FGFR4
Daichi Sanyo
TOPO-1
GPR20
Adriamycin + Gleevec
Pharmacia & Upjohn + Novartis
KIT
PDGFRA
Bcr-Abl
Liporaxel
Dae Hwa Pharmaceutical
Tubulin
Deciphera
ULK1/2
Deciphera
ULK1/2
KIT
Deciphera
QINLOCK
Deciphera Pharmaceuticals, LLC
KIT
PDGFRA
VEGFR2
TIE-2
Fms/CSF-1
BRAF
PDGFRB
PDK
PDKII
Sprycel + Avastin
Bristol Myers-Squibb + Genetech
KIT
BCR-ABL
PDGFRB
SRC family
EPHA2
VEGFA (Bevacizumab)
Ayvakit
Blueprint Medicines Corporation
PDGFRA (D842V)
KIT exon 17
KIT D816V
CStone Pharmaceuticals
PD-L1
Gleevec, Sutent
Daiichi Sankyo
DR5 (TRAIL-R2) (CS-1008)
KIT (imatinib & sunitinib)
PDGFRA (imatinib & sunitinib)
Bcr-abl
VEGFRs (sunitinib)
FLT3 (sunitinib)
CSF-1R (sunitinib)
RET (sunitinib)
Cornerstone Pharmaceuticals
α-ketoglutarate dehydrogenase (KGDH)
Pyruvate dehydrogenase (PDH)
AstraZeneca
CTLA-4
Arog Pharmaceuticals
PDGFRA
PDGFRB
PDGFRA (D842V)
FLT3
Pfizer
IGF1R
ChemGenex Pharmaceuticals
80S ribosome
Cogent Biosciences
KIT
Cogent Bioscience
KIT
Cogent Biosciences
KIT Exon 17
Torisel
Wheth Pharmaceuticals
mTOR
Calithera Biosciences, Inc
Glutaminase (GLS)
Calithera & Pfizer
Glutaminase (GLS)
PARP1
PARP2
Novartis
PI3K Class 1A
Velcade + Sutent
Millennium
KIT (sunitinib)
PDGFRA (sunitinib)
PDGFRB (sunitinib)
VEGFRs (sunitinib)
RET (sunitinib)
SCF-1R (sunitinib)
CSF-1R (sunitinib)
26S proteasome (bortezomib)
Bristol-Myers Squibb
LAG-3
Bristol-Myers Squibb
Opdivo
Bristol-Myers Squibb
PD-1
Bristol-Myers Squibb
IGF-1R
Bristol-Myers Squibb
VEGFR2
FGFR
Sprycel
Bristol-Myers Squibb
KIT
bcr-abl
SRC family
PDGFRB
EPHA2
LCK
YES
FYN
SRC
Bristol-Myers Squibb
IGF1R
Talzenna
Pfizer
PARP1
PARP2
AYVAKIT
Blueprint Medicines
PDGFRA (D842V)
KIT exon 17
KIT D816V
Novartis
PI3K Class 1
MEK 1/2
Novartis + GlaxoSmithKline
MEK 1/2
PI3K Class 1A
Novartis
PI3K Class 1
Biogen Idec
HSP90
Biogen Idec
HSP90
Biogen Idec
IGF1R
Novartis
PI3K
mTOR
Novartis
FGFR
FGFR1
FGFR2
FGFR3
VEGFR2
BerGenBio
AXL
Novartis
PI3K Class 1
mTOR Raptor
mTOR Rictor
MEK 1/2
Novartis
PI3K Class I
mTOR Raptor
mTOR Rictor
Avastin
Genentech Bio-oncology
VEGF-A
Boston Biomedical
NANOG
Bayer
MEK
Bayer
PI3K
MEK
Bayer
PI3K
Stivarga
Bayer
Raf-1
BRAF
VEGRF2
VEGFR3
KIT
PDGFRA
PDGFRB
RET
TIE-2
DDR-2
FGFR1
FGFR2
Trk2A
Eph2A
BRAF V600E
SAPK2
PTK5
Abl
Bayer/ACT BIOTECH
KIT
VEGFR2
VEGFR3
PDGFRB
Nexavar + Avastin
Bayer and Genentech
KIT (Sorafenib)
PDGFR (Sorafenib)
VEGFR (Sorafenib)
VEGFR (Bevacizumab)
BRAF (Sorafenib)
mutant BRAF (Sorafenib)
CRAF
Nexavar
Bayer
KIT
Raf-1
PDGFRB
BRAF
Mutant BRAF
FLT3
VEGFR
Bayer
FGFR1
FGFR2
FGFR3
FGFR4
MEK 1/2
mTOR (CCI-779)
Array Biopharma/AstraZeneca
MEK 1/2
Recentin
AstraZeneca
VEGFR1
VEGFR2
VEGFR3
KIT
PDGFRA
PDGFRB
AVEO Pharmaceuticals, Inc.
VEGFR-1, 2, 3
KIT
PDGFRB
Novartis
HSP90
Astex Therapeutics, Ltd.
HSP90
ArQule
AKT
Iclusig
ARIAD
Bcr-Abl
KIT
PDGFRA
VEGFR
FLT3
FGFR
EPH
SRC family
RET
TIE-2
ARIAD
mTOR
Tasigna
Novartis
DDR-1
DDR-2
Bcr-Abl
PDGFRA
PDGFRB
KIT
MAPK11
MAPK12
ZAK
Amgen
VEGFR1
VEGFR2
VEGFR3
KIT
Amgen
KRAS G12C
Amgen
IGF-1R (AMG 479)
DR5 (Death receptor 5) (AMG 655)
Amgen
IGF1R
Advenchen Laboratories
KIT
PDGFRa
VEGFR2
VEGFR3
Inlyta
Pfizer
VEGFR-1, 2, 3
KIT
PDGFRA
T315I (BCR-ABL gatekeeper mutation)
Novartis
PKC theta
PKC alpha
PKC beta
Abbott
BCL-2
AB Science
KIT
PDGFR
FGFR3
Lyn
Advanced Accelerator Aplications
GRPR
Advanced Accelerator Applications
None, Adriamycin
Aventis,
Gemzar, Taxotere
Cobra Biomanufacturing Plc
CD8 and CD4 positive T-cells
Temodar
Schering-Plough
DNA methylation
Tasigna + Gleevec
Novartis
Votrient + Zolinza
GlaxoSmithKline & Merck
KIT (pazopanib)
PDGFRA (pazopanib)
PDGFRB (pazopanib)
VEGFRS (pazopanib)
HDAC (vorinostat)
Votrient + Hycamtin
GlaxoSmithKline
KIT (pazopanib)
PDGFRA (pazopanib)
PDGFRB (pazopanib)
VEGFRS (pazopanib)
Topoisomerase I (topetecan)
GlaxoSmithKline
KIT (pazopanib)
MEK (Trametinib)
VEGFRS (pazopanib)
PDGFRA (pazopanib)
Novartis
GlaxoSmithKline
Gleevec + Dovitinib
Novartis
Hoffman-La Roche
Glivec + Stivarga
Novartis + Bayer
Plexxicon + Merck
Opdivo + Yervoy
Bristol-Myers Squibb
PD-1
CTLA-4
Tafinlar + Mekinist
GlaxoSmithKline
BRAF V600E
BRAF V600K
MEK 1/2
Inlyta + Keytruda
Pfizer + Merck
KIT
PDGFRa
VEGFR-1, 2, 3
T315I (BCR-ABL gatekeeper mutation)
PD-1
Intuvax
Immunicum
CD8 and CD4 positive T-cells
Tumor antigens
BCL-2
KIT
Raf-1
PDGFRB
BRAF
mutant BRAF
FLT3
VEGFR
MEK1/2
KIT
FLT3
Fms/CSF-1
CSF-1R
PD-L1
CTLA-4
Merck + Incyte
PD-1
IDO1

255 drugs found

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