Drug Detail

Information about ddPCR

Generic Name	ddPCR
IND	ddPCR
Brand Name (US)
Manufacturer
Drug Type
Delivery	Circulating tumor DNA
Approval Status
Indications
Overall Strategy	Resistance mutation assay for targeted therapy
Strategy	Targeted therapy
Drug Category	none

Digital Drop Polymerase Chain Reaction Assay for monitoring imatinib resistant KIT mutations

Links
	Development of Highly Sensitive Digital Droplet PCR for Detection of cKIT Mutations in Circulating Free DNA That Mediate Resistance to TKI Treatment for Gastrointestinal Stromal Tumor (GIST)

Trials of this drug
	Detection of CF-DNA in Patients With Gastrointestinal Stromal Tumors (GIST)

	Cross-Platform Biomarker Program for Establishment and Validation of Liquid Biopsy for Clinical Decision Making in resectable gastrointestinal stromal tumour (GIST)

Trial results
	Int J Mol Sci 3/12/2023 Bubnoff, N "Development of Highly Sensitive Digital Droplet PCR for Detection of cKIT Mutations in Circulating Free DNA That Mediate Resistance to TKI Treatment for Gastrointestinal Stromal Tumor (GIST)"

	Intl Journ Nol Sci 3/12/2023 Bubnoff, N "Development of Highly Sensitive Digital Droplet PCR for Detection of cKIT Mutations in Circulating Free DNA That Mediate Resistance to TKI Treatment for Gastrointestinal Stromal Tumor (GIST)"