Drug Watch List

Note: Some of these drugs are not in trials yet or are not in trials that we are monitoring for GIST.
Note: Click on a column title to sort the list  

255 drugs found

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Targets
ImClone
PDGFRA
Ignyta
TrkA
TrkB
TrkC
ROS1
ALK
NTRK
IDRx, Inc.
KIT V654A
PDGFRa V651D
Hoffmann-La Roche
IGF1R
Hoffman-La Roche
gama-secretase
Hoffman-La Roche
PD-L1
Hoffman-La Roche
GSK
IGF1R
Istodax
Gloucester Pharmaceuticals
HDAC
Votrient + Zolinza
GlaxoSmithKline & Merck
KIT (pazopanib)
PDGFRA (pazopanib)
PDGFRB (pazopanib)
VEGFRS (pazopanib)
HDAC (vorinostat)
Votrient
GlaxoSmithKline
KIT
VEGFR-1, 2, 3
PDGFRA
PDGFRB
Itk
LCK
c-Fms
FGFR -1 and -3
Votrient + Hycamtin
GlaxoSmithKline
KIT (pazopanib)
PDGFRA (pazopanib)
PDGFRB (pazopanib)
VEGFRS (pazopanib)
Topoisomerase I (topetecan)
TAFINLAR
GlaxoSmithKline
BRAF
BRAF V600E
BRAF V600K
Mekinist
GlaxoSmithKline
MEK1
MEK2
GlaxoSmithKline
KIT (pazopanib)
MEK (Trametinib)
VEGFRS (pazopanib)
PDGFRA (pazopanib)
GlaxoSmithKline
Tafinlar + Mekinist
GlaxoSmithKline
BRAF V600E
BRAF V600K
MEK 1/2
Genentech/Piramed Ltd.
PI3K
mTOR
Genentech/Exelixis
MEK
Genentech/Amgen
DR4 (Death receptor 4)
DR5 (Death receptor 5)
Avastin
Genentech Bio-oncology
VEGF-A
Genentech
PI3K
MEK
Erivedge
Genentech
SMO (smoothened receptor)
Genentech
Genentech
Genentech
IDO1
Exelixis
KIT
VEGFR2
PDGFRB
Exelixis
PI3K Class I
mTOR Raptor
mTOR Rictor
DNA-PK
Exelixis
PI3K Class I
Exelixis
IGF1R
Scr
FGFR
Bcr-Abl
Cometriq
Exelixis
c-MET
VEGFR-1, 2, 3
RET
KIT
FLT3
TEK
AXL
TRKB
TIE-2
EntreMed
Aurora Kinase A
Aurora Kinase B
VEGFR2
KIT
FGFR1
EMD Serono
EMD Serono
EMD Serono
Lenvima
Eisai Co.
KIT
PDGFRa
VEGFR1
VEGFR2
VEGFR3
RET
FGFR1
FGFR2
FGFR3
FGFR4
Edo
QINLOCK
Deciphera Pharmaceuticals, LLC
KIT
PDGFRA
VEGFR2
TIE-2
Fms/CSF-1
BRAF
PDGFRB
Deciphera / Array
Deciphera
ULK1/2
Deciphera
ULK1/2
KIT
Deciphera
Gleevec, Sutent
Daiichi Sankyo
DR5 (TRAIL-R2) (CS-1008)
KIT (imatinib & sunitinib)
PDGFRA (imatinib & sunitinib)
Bcr-abl
VEGFRs (sunitinib)
FLT3 (sunitinib)
CSF-1R (sunitinib)
RET (sunitinib)
Daichi Sanyo
TOPO-1
GPR20
Liporaxel
Dae Hwa Pharmaceutical
Tubulin
CStone Pharmaceuticals
PD-L1
CStone Pharmaceuticals
PDL-1
KIT
PDGFRa
Cornerstone Pharmaceuticals
α-ketoglutarate dehydrogenase (KGDH)
Pyruvate dehydrogenase (PDH)
Cogent Biosciences
KIT
Cogent Biosciences
KIT
FLT3
CSF-1R
Cogent Biosciences
KIT Exon 17
Cogent Bioscience
KIT
Cobra Biomanufacturing Plc
CD8 and CD4 positive T-cells
ChemGenex Pharmaceuticals
80S ribosome
Calithera Biosciences, Inc
Glutaminase (GLS)
Calithera & Pfizer
Glutaminase (GLS)
PARP1
PARP2
Sprycel + Yervoy
Bristol-Myers Squibb (both)
CTLA-4 (ipilimumab)
KIT (dasatinib)
PDGFRB (dasatinib)
bcr-abl (dasatinib)
SCR (dasatinib)
EPHA2 (dasatinib)
LCK (dasatinib)
YES (dasatinib)
FYN (dasatinib)
Bristol-Myers Squibb
VEGFR2
FGFR
Sprycel
Bristol-Myers Squibb
KIT
bcr-abl
SRC family
PDGFRB
EPHA2
LCK
YES
FYN
SRC
Bristol-Myers Squibb
IGF1R
Bristol-Myers Squibb
IGF-1R
Yervoy
Bristol-Myers Squibb
CTLA-4
Opdivo
Bristol-Myers Squibb
PD-1
Bristol-Myers Squibb
LAG-3
Bristol-Myers Squibb
Opdivo + Yervoy
Bristol-Myers Squibb
PD-1
CTLA-4
Sprycel + Avastin
Bristol Myers-Squibb + Genetech
KIT
BCR-ABL
PDGFRB
SRC family
EPHA2
VEGFA (Bevacizumab)
Boston Biomedical
NANOG
Ayvakit
Blueprint Medicines Corporation
PDGFRA (D842V)
KIT exon 17
KIT D816V
AYVAKIT
Blueprint Medicines
PDGFRA (D842V)
KIT exon 17
KIT D816V
Biogen Idec
HSP90
Biogen Idec
IGF1R
Biogen Idec
HSP90
BerGenBio
AXL
Bayer/ACT BIOTECH
KIT
VEGFR2
VEGFR3
PDGFRB
Bayer, Merck
KIT
PD-L1
Nexavar + Avastin
Bayer and Genentech
KIT (Sorafenib)
PDGFR (Sorafenib)
VEGFR (Sorafenib)
VEGFR (Bevacizumab)
BRAF (Sorafenib)
mutant BRAF (Sorafenib)
CRAF
Nexavar
Bayer
KIT
Raf-1
PDGFRB
BRAF
Mutant BRAF
FLT3
VEGFR
Stivarga
Bayer
Raf-1
BRAF
VEGRF2
VEGFR3
KIT
PDGFRA
PDGFRB
RET
TIE-2
DDR-2
FGFR1
FGFR2
Trk2A
Eph2A
BRAF V600E
SAPK2
PTK5
Abl
Bayer
PI3K
Bayer
MEK
Bayer
PI3K
MEK
Stivarga
Bayer
MEK
Bayer
FGFR1
FGFR2
FGFR3
FGFR4
AVEO Pharmaceuticals, Inc.
VEGFR-1, 2, 3
KIT
PDGFRB
None, Adriamycin
Aventis,
Aventis
Recentin
AstraZeneca
VEGFR1
VEGFR2
VEGFR3
KIT
PDGFRA
PDGFRB
Caprelsa
AstraZeneca
EGFR
VEGFR
AstraZeneca
CTLA-4
Astex Therapeutics, Ltd.
HSP90
Gleevec + AT13387
Astex Therapeutics
KIT (Gleevec)
PDGFRA (Gleevec)
Bcr-Abl (Gleevec)
Hsp90 (AT13387)
Astex Pharmaceuticals
Ascentage Pharma
Bcr-Abl
KIT
Array Biopharma/AstraZeneca
MEK 1/2
BRAFTOVI
Array Biopharma
BRAF V600E
BRAF V600K
ArQule
AKT
Arog Pharmaceuticals
PDGFRA
PDGFRB
PDGFRA (D842V)
FLT3
ARIAD
mTOR
Iclusig
ARIAD
Bcr-Abl
KIT
PDGFRA
VEGFR
FLT3
FGFR
EPH
SRC family
RET
TIE-2
Amgen
VEGFR1
VEGFR2
VEGFR3
KIT
Amgen
IGF1R
Amgen
IGF-1R (AMG 479)
DR5 (Death receptor 5) (AMG 655)
Amgen
KRAS G12C
Advenchen Laboratories
KIT
PDGFRa
VEGFR2
VEGFR3
Advanced Accelerator Applications
Advanced Accelerator Aplications
GRPR
Venclexta
Abbvie / Genetech
BCL-2
Abbott
BCL-2
AB Science
KIT
PDGFR
FGFR3
Lyn
PDK
PDKII
Gemzar, Taxotere
HDAC (vorinostat)
26S proteasome (bortezomib)
MEK 1/2
mTOR (CCI-779)

255 drugs found

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