Drug Watch List

Note: Some of these drugs are not in trials yet or are not in trials that we are monitoring for GIST.
Note: Click on a column title to sort the list  

249 drugs found

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Targets
Gleevec
Novartis
KIT
bcr-abl
abl
PDGFRA
PDGFRB
Sutent
Pfizer
KIT
PDGFRA
PDGFRB
VEGFR1
VEGFR2
VEGFR3
FLT3
CSF-1R
RET
Stivarga
Bayer
Raf-1
BRAF
VEGRF2
VEGFR3
KIT
PDGFRA
PDGFRB
RET
TIE-2
DDR-2
FGFR1
FGFR2
Trk2A
Eph2A
BRAF V600E
SAPK2
PTK5
Abl
QINLOCK
Deciphera Pharmaceuticals, LLC
KIT
PDGFRA
VEGFR2
TIE-2
Fms/CSF-1
BRAF
PDGFRB
AYVAKIT
Blueprint Medicines
PDGFRA (D842V)
KIT exon 17
KIT D816V
Cometriq
Exelixis
c-MET
VEGFR-1, 2, 3
RET
KIT
FLT3
TEK
AXL
TRKB
TIE-2
Plexxicon
KIT
FLT3
Fms/CSF-1
CSF-1R
Plexxicon + Merck
Cogent Biosciences
KIT
FLT3
CSF-1R
Cogent Bioscience
KIT
IDRx, Inc.
KIT V654A
PDGFRa V651D
Tasigna
Novartis
DDR-1
DDR-2
Bcr-Abl
PDGFRA
PDGFRB
KIT
MAPK11
MAPK12
ZAK
Sutent + Stivarga
Pfizer + Bayer
CStone Pharmaceuticals
PD-L1
CStone Pharmaceuticals
PDL-1
KIT
PDGFRa
Nexavar
Bayer
KIT
Raf-1
PDGFRB
BRAF
Mutant BRAF
FLT3
VEGFR
Iclusig
ARIAD
Bcr-Abl
KIT
PDGFRA
VEGFR
FLT3
FGFR
EPH
SRC family
RET
TIE-2
Votrient
GlaxoSmithKline
KIT
VEGFR-1, 2, 3
PDGFRA
PDGFRB
Itk
LCK
c-Fms
FGFR -1 and -3
Sprycel
Bristol-Myers Squibb
KIT
bcr-abl
SRC family
PDGFRB
EPHA2
LCK
YES
FYN
SRC
Kolltan
Kit
AB Science
KIT
PDGFR
FGFR3
Lyn
Opdivo
Bristol-Myers Squibb
PD-1
Astex Pharmaceuticals
Arog Pharmaceuticals
PDGFRA
PDGFRB
PDGFRA (D842V)
FLT3
Bristol-Myers Squibb
LAG-3
Bristol-Myers Squibb
Inlyta
Pfizer
VEGFR-1, 2, 3
KIT
PDGFRA
T315I (BCR-ABL gatekeeper mutation)
GlaxoSmithKline
Sprycel + Yervoy
Bristol-Myers Squibb (both)
CTLA-4 (ipilimumab)
KIT (dasatinib)
PDGFRB (dasatinib)
bcr-abl (dasatinib)
SCR (dasatinib)
EPHA2 (dasatinib)
LCK (dasatinib)
YES (dasatinib)
FYN (dasatinib)
Rapamune
Wyeth
mTOR
Genentech/Piramed Ltd.
PI3K
mTOR
Pfizer
PD-L1
KIT
Ayvakit
Blueprint Medicines Corporation
PDGFRA (D842V)
KIT exon 17
KIT D816V
Lenvima
Eisai Co.
KIT
PDGFRa
VEGFR1
VEGFR2
VEGFR3
RET
FGFR1
FGFR2
FGFR3
FGFR4
KIT
PDGFRa
XPO1
Advenchen Laboratories
KIT
PDGFRa
VEGFR2
VEGFR3
Taxol
Pfizer
Tubulin
Novartis
KIT
PD-1
Ascentage Pharma
Bcr-Abl
KIT
Bayer, Merck
KIT
PD-L1
Stivarga
Bayer
MEK
Daichi Sanyo
TOPO-1
GPR20
Bayer
FGFR1
FGFR2
FGFR3
FGFR4
Ningbo Newbay
KIT
PDGFRA
cKit
PDGFRa
VEGFR2
VEGFR3
FLT1
FLT3
Deciphera / Array
Theseus
KIT
PDGFRa
Cogent Biosciences
KIT Exon 17
Advanced Accelerator Applications
Inhibrx, Inc.
DR5 (Death receptor 5)
Inhibrx, Inc.
DR5 (Death receptor 5)
DR5 (Death receptor 5)
Taiho Phrmaceutical Co.
KIT
PDGFRa
PD-L1
HIF2A
Deciphera
ULK1/2
Deciphera
ULK1/2
KIT
Rivoceranib
Jiangsu Hengrui Medicine
VEGFR2
Ibrance
Pfizer
Cdk4
Cdk6
Novartis
KIT
PDGFR
VEGFR1
VEGFR2
VEGFR3
FGFR1
FGFR2
FGFR3
FLT3
RET
TrkA
CSF-1R
Gleevec + AT13387
Astex Therapeutics
KIT (Gleevec)
PDGFRA (Gleevec)
Bcr-Abl (Gleevec)
Hsp90 (AT13387)
Afinitor/Certican
Novartis
mTOR
Gleevec
Novartis + Novartis
HDAC
KIT
PDGFRA
PDGFRB
Bcr-Abl
Opdivo + Yervoy
Bristol-Myers Squibb
PD-1
CTLA-4
Tafinlar + Mekinist
GlaxoSmithKline
BRAF V600E
BRAF V600K
MEK 1/2
Inlyta + Keytruda
Pfizer + Merck
KIT
PDGFRa
VEGFR-1, 2, 3
T315I (BCR-ABL gatekeeper mutation)
PD-1
Intuvax
Immunicum
CD8 and CD4 positive T-cells
Tumor antigens
ArQule
AKT
Ignyta
TrkA
TrkB
TrkC
ROS1
ALK
NTRK
Loxo Oncology
TrkA
TrkB
TrkC
NTRK
Abbott
BCL-2
BCL-2
KIT
Raf-1
PDGFRB
BRAF
mutant BRAF
FLT3
VEGFR
Advanced Accelerator Aplications
GRPR
MEK1/2
KIT
FLT3
Fms/CSF-1
CSF-1R
Venclexta
Abbvie / Genetech
BCL-2
Keytruda + Cyclophosphamide
PD-1
CD4+ Treg
CD8+ Treg
AstraZeneca
CTLA-4
PD-L1
CTLA-4
Merck + Incyte
PD-1
IDO1
Incyte
Mundipharma-EDO Gmbh
Histone-deacetylase
Xencor
SSTR2
CD3
PharmaMar
Tubulin
Edo
Peloton
HIF-2a
Talzenna
Pfizer
PARP1
PARP2
Calithera & Pfizer
Glutaminase (GLS)
PARP1
PARP2
Cogent Biosciences
KIT
Amgen
KRAS G12C
Taiho Pharmaceuticals
HSP90 subtype alpha HSP90 subtype beta
Hoffman-La Roche
PD-L1
Hoffman-La Roche
Glivec + Stivarga
Novartis + Bayer
Keytruda
Merck
PD-1
Novartis
PD-1
ISA Pharmaceuticals
Novartis
Medimmune
PD-L1
B7H1
Stanford University
CD47
Gleevec + Afinitor
Novartis, Novartis
KIT
PDGFRA
Bcr-Abl
mTOR
Calithera Biosciences, Inc
Glutaminase (GLS)
Gleevec + Dovitinib
Novartis
Boston Biomedical
NANOG
Novartis
VEGFR1
VEGFR2
VEGFR3
KIT
PDGFRB
Farydak
Novartis
HDAC
Novartis
KIT (Gleevec)
PDGFRA (Gleevec)
Bcr-Abl (Gleevec)
PI3K (BKM120)
Synta
HSP90
Gleevec + PEG-Intron
Novartis, Schering
KIT
PDGFRA
Bcr-Abl
Novartis
KIT
Yervoy
Bristol-Myers Squibb
CTLA-4
Zolinza
Merck
HDAC
Bayer/ACT BIOTECH
KIT
VEGFR2
VEGFR3
PDGFRB
ARIAD
mTOR
BRAFTOVI
Array Biopharma
BRAF V600E
BRAF V600K
Gleevec + Proleukin
Novartis + Novartis
KIT (Gleevec)
Bcr-Abl (imatinib)
PDGFRA (Gleevec)
Interleukin-2 (IL-2)
Zelboraf
Plexxicon
BRAF V600E
Oncothyreon
HIF-1α
OSI
IGF1R
IR (insulin receptor)

249 drugs found

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