Drug Watch List

Note: Some of these drugs are not in trials yet or are not in trials that we are monitoring for GIST.
Note: Click on a column title to sort the list  

259 drugs found

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Targets
PDK
PDKII
Gemzar, Taxotere
HDAC (vorinostat)
26S proteasome (bortezomib)
MEK 1/2
mTOR (CCI-779)
Tumor antigens
BCL-2
KIT
Raf-1
PDGFRB
BRAF
mutant BRAF
FLT3
VEGFR
MEK1/2
KIT
FLT3
Fms/CSF-1
CSF-1R
Keytruda + Cyclophosphamide
PD-1
CD4+ Treg
CD8+ Treg
PD-L1
CTLA-4
KIT
PDGFRa
XPO1
cKit
PDGFRa
VEGFR2
VEGFR3
FLT1
FLT3
KIT
PDGFRa
PD-L1
HIF2A
KIT
PDGFRA
Menin-MLL
MSI-H
dMMR
AB Science
KIT
PDGFR
FGFR3
Lyn
Abbott
BCL-2
Venclexta
Abbvie / Genetech
BCL-2
Advanced Accelerator Aplications
GRPR
Advanced Accelerator Applications
Advenchen Laboratories
KIT
PDGFRa
VEGFR2
VEGFR3
Amgen
VEGFR1
VEGFR2
VEGFR3
KIT
Amgen
IGF1R
Amgen
IGF-1R (AMG 479)
DR5 (Death receptor 5) (AMG 655)
Amgen
KRAS G12C
ARIAD
mTOR
Iclusig
ARIAD
Bcr-Abl
KIT
PDGFRA
VEGFR
FLT3
FGFR
EPH
SRC family
RET
TIE-2
Arog Pharmaceuticals
PDGFRA
PDGFRB
PDGFRA (D842V)
FLT3
ArQule
AKT
BRAFTOVI
Array Biopharma
BRAF V600E
BRAF V600K
Array Biopharma/AstraZeneca
MEK 1/2
Ascentage Pharma
Bcr-Abl
KIT
Astex Pharmaceuticals
Gleevec + AT13387
Astex Therapeutics
KIT (Gleevec)
PDGFRA (Gleevec)
Bcr-Abl (Gleevec)
Hsp90 (AT13387)
Astex Therapeutics, Ltd.
HSP90
Recentin
AstraZeneca
VEGFR1
VEGFR2
VEGFR3
KIT
PDGFRA
PDGFRB
Caprelsa
AstraZeneca
EGFR
VEGFR
AstraZeneca
CTLA-4
Aventis
None, Adriamycin
Aventis,
AVEO Pharmaceuticals, Inc.
VEGFR-1, 2, 3
KIT
PDGFRB
Stivarga
Bayer
Raf-1
BRAF
VEGRF2
VEGFR3
KIT
PDGFRA
PDGFRB
RET
TIE-2
DDR-2
FGFR1
FGFR2
Trk2A
Eph2A
BRAF V600E
SAPK2
PTK5
Abl
Bayer
PI3K
Bayer
MEK
Bayer
PI3K
MEK
Stivarga
Bayer
MEK
Bayer
FGFR1
FGFR2
FGFR3
FGFR4
Nexavar
Bayer
KIT
Raf-1
PDGFRB
BRAF
Mutant BRAF
FLT3
VEGFR
Nexavar + Avastin
Bayer and Genentech
KIT (Sorafenib)
PDGFR (Sorafenib)
VEGFR (Sorafenib)
VEGFR (Bevacizumab)
BRAF (Sorafenib)
mutant BRAF (Sorafenib)
CRAF
Bayer, Merck
KIT
PD-L1
Bayer/ACT BIOTECH
KIT
VEGFR2
VEGFR3
PDGFRB
BerGenBio
AXL
Biogen Idec
HSP90
Biogen Idec
IGF1R
Biogen Idec
HSP90
AYVAKIT
Blueprint Medicines
PDGFRA (D842V)
KIT exon 17
KIT D816V
Ayvakit
Blueprint Medicines Corporation
PDGFRA (D842V)
KIT exon 17
KIT D816V
Boston Biomedical
NANOG
Sprycel + Avastin
Bristol Myers-Squibb + Genetech
KIT
BCR-ABL
PDGFRB
SRC family
EPHA2
VEGFA (Bevacizumab)
Bristol-Myers Squibb
VEGFR2
FGFR
Sprycel
Bristol-Myers Squibb
KIT
bcr-abl
SRC family
PDGFRB
EPHA2
LCK
YES
FYN
SRC
Bristol-Myers Squibb
IGF1R
Bristol-Myers Squibb
IGF-1R
Yervoy
Bristol-Myers Squibb
CTLA-4
Opdivo
Bristol-Myers Squibb
PD-1
Bristol-Myers Squibb
LAG-3
Bristol-Myers Squibb
Opdivo + Yervoy
Bristol-Myers Squibb
PD-1
CTLA-4
Bristol-Myers Squibb
PRMT5
Sprycel + Yervoy
Bristol-Myers Squibb (both)
CTLA-4 (ipilimumab)
KIT (dasatinib)
PDGFRB (dasatinib)
bcr-abl (dasatinib)
SCR (dasatinib)
EPHA2 (dasatinib)
LCK (dasatinib)
YES (dasatinib)
FYN (dasatinib)
Calithera & Pfizer
Glutaminase (GLS)
PARP1
PARP2
Calithera Biosciences, Inc
Glutaminase (GLS)
ChemGenex Pharmaceuticals
80S ribosome
Cobra Biomanufacturing Plc
CD8 and CD4 positive T-cells
Cogent Bioscience
KIT
Cogent Biosciences
KIT
Cogent Biosciences
KIT
FLT3
CSF-1R
Cogent Biosciences
KIT Exon 17
Cornerstone Pharmaceuticals
α-ketoglutarate dehydrogenase (KGDH)
Pyruvate dehydrogenase (PDH)
CStone Pharmaceuticals
PD-L1
CStone Pharmaceuticals
PDL-1
KIT
PDGFRa
Liporaxel
Dae Hwa Pharmaceutical
Tubulin
Daichi Sanyo
TOPO-1
GPR20
Gleevec, Sutent
Daiichi Sankyo
DR5 (TRAIL-R2) (CS-1008)
KIT (imatinib & sunitinib)
PDGFRA (imatinib & sunitinib)
Bcr-abl
VEGFRs (sunitinib)
FLT3 (sunitinib)
CSF-1R (sunitinib)
RET (sunitinib)
Deciphera
ULK1/2
Deciphera
ULK1/2
KIT
Deciphera
Deciphera / Array
QINLOCK
Deciphera Pharmaceuticals, LLC
KIT
PDGFRA
VEGFR2
TIE-2
Fms/CSF-1
BRAF
PDGFRB
Edo
Lenvima
Eisai Co.
KIT
PDGFRa
VEGFR1
VEGFR2
VEGFR3
RET
FGFR1
FGFR2
FGFR3
FGFR4
EMD Serono
EMD Serono
EMD Serono
EntreMed
Aurora Kinase A
Aurora Kinase B
VEGFR2
KIT
FGFR1
Exelixis
KIT
VEGFR2
PDGFRB
Exelixis
PI3K Class I
mTOR Raptor
mTOR Rictor
DNA-PK
Exelixis
PI3K Class I
Exelixis
IGF1R
Scr
FGFR
Bcr-Abl
Cometriq
Exelixis
c-MET
VEGFR-1, 2, 3
RET
KIT
FLT3
TEK
AXL
TRKB
TIE-2
Genentech
PI3K
MEK
Erivedge
Genentech
SMO (smoothened receptor)
Genentech
Genentech
Genentech
IDO1
Avastin
Genentech Bio-oncology
VEGF-A
Genentech/Amgen
DR4 (Death receptor 4)
DR5 (Death receptor 5)
Genentech/Exelixis
MEK

259 drugs found

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