Drug Watch List

Note: Some of these drugs are not in trials yet or are not in trials that we are monitoring for GIST.
Note: Click on a column title to sort the list  

265 drugs found

Targets

Inlyta + Keytruda
Pfizer + Merck
KIT
PDGFRa
VEGFR-1, 2, 3
T315I (BCR-ABL gatekeeper mutation)
PD-1

Sutent + Stivarga
Pfizer + Bayer

Sutent
Pfizer, Pfizer
KIT (sunitinib)
PDGFRA (sunitinib)
PDGFRB (sunitinib)
IGF1R (CP-751,871)
VEGFR1 (sunitinib)
VEGFR2 (sunitinib)
VEGFR3 (sunitinib)
FLT3 (sunitinib)
SCF-1R (sunitinib)
RET (sunitinib)

Sutent + TH-302
Pfizer, Threshold Pharmaceuticals
KIT (sunitinib)
PDGFRA (sunitinib)
VEGFRs (sunitinib)
Hypoxia (TH-302)

Adriamycin + Gleevec
Pharmacia & Upjohn + Novartis
KIT
PDGFRA
Bcr-Abl

PharmaMar
Tubulin

Phoenix Biotechnology, Inc.
α-3 subunit of Na-K ATPase pump

Piramed
PI3K Class 1

Zelboraf
Plexxicon
BRAF V600E

Plexxicon
KIT
FLT3
Fms/CSF-1
CSF-1R

Plexxicon + Merck

Roche
MDM2

Temodar
Schering-Plough
DNA methylation

Schering-Plough
IGF1R

Semafore
PI3K Class 1A
DNA-PK
mTOR
Polo-like 1 kinases
PIM1
CK2

Serenex
HSP90

Stanford University
CD47

Synta
HSP90

Jeselhy
Taiho Pharmaceuticals
HSP90 subtype alpha HSP90 subtype beta

Jeselhy
Taiho Phrmaceutical Co.

Theseus
KIT
PDGFRa

Topo/Target A/S

Torisel
Wheth Pharmaceuticals
mTOR

Rapamune
Wyeth
mTOR

Xencor
SSTR2
CD3

265 drugs found