Drug Watch List

Note: Some of these drugs are not in trials yet or are not in trials that we are monitoring for GIST.
Note: Click on a column title to sort the list  

259 drugs found

Targets

Gleevec, Sutent
Novartis, Pfizer
KIT (imatinib & sunitinib)
PDGFRA (imatinib & sunitinib)
Bcr-Abl (imatinib)
VEGFR1 (sunitinib)
VEGFR2 (sunitinib)
VEGFR3 (sunitinib)
FLT3 (sunitinib)
CSR-1R (sunitinib)
RET (sunitinib)

Sutent
Pfizer
KIT
PDGFRA
PDGFRB
VEGFR1
VEGFR2
VEGFR3
FLT3
CSF-1R
RET

Sutent + Stivarga
Pfizer + Bayer

Sutent
Pfizer, Pfizer
KIT (sunitinib)
PDGFRA (sunitinib)
PDGFRB (sunitinib)
IGF1R (CP-751,871)
VEGFR1 (sunitinib)
VEGFR2 (sunitinib)
VEGFR3 (sunitinib)
FLT3 (sunitinib)
SCF-1R (sunitinib)
RET (sunitinib)

Sutent + TH-302
Pfizer, Threshold Pharmaceuticals
KIT (sunitinib)
PDGFRA (sunitinib)
VEGFRs (sunitinib)
Hypoxia (TH-302)

Novartis
IGF-1R
FAK

Taiho Pharmaceuticals
HSP90 subtype alpha HSP90 subtype beta

Theseus
KIT
PDGFRa

Novartis
KIT
PDGFR
VEGFR1
VEGFR2
VEGFR3
FGFR1
FGFR2
FGFR3
FLT3
RET
TrkA
CSF-1R

Zolinza + Nexavar
Merck + Bayer
KIT
PDGFRA
PDGFRB
BRAF
Mutant BRAF
CRAF
VEGFR
HDAC (vorinostat)

HDAC (vorinostat)
26S proteasome (bortezomib)

Cometriq
Exelixis
c-MET
VEGFR-1, 2, 3
RET
KIT
FLT3
TEK
AXL
TRKB
TIE-2

Exelixis
IGF1R
Scr
FGFR
Bcr-Abl

Exelixis
PI3K Class I

Exelixis
PI3K Class I
mTOR Raptor
mTOR Rictor
DNA-PK

Exelixis
KIT
VEGFR2
PDGFRB

Xencor
SSTR2
CD3

Rivoceranib
Jiangsu Hengrui Medicine
VEGFR2

Caprelsa
AstraZeneca
EGFR
VEGFR

259 drugs found