TRIAL DETAIL

A Phase 3 Study to Evaluate Efficacy and Safety of Masitinib in Comparison to Imatinib in Patients With Gastro-Intestinal Stromal Tumour in First Line Medical Treatment

Drug:
Trial Name:
A Phase 3 Study to Evaluate Efficacy and Safety of Masitinib in Comparison to Imatinib in Patients With Gastro-Intestinal Stromal Tumour in First Line Medical Treatment
NCT#:
Conditions:
Gastrointestinal Stromal Tumor
Status:
Unknown
Phase:
3
Start Date 12/01/2008
Age of Trial (yrs) 13
Treatment Phase:
First-line
Drug Category:
KIT/PDGFRA inhibitor
Strategy:
Block KIT
Trial Type:
Specifically GIST and only GIST
Other Protocol IDs:
AB04030
Sponsor:
AB Science
Patient Contact:
Centre Oscar Lambret Antoine Adenis, M.D. a-adenis@o-lambret.fr +33 (0)3 20 29 59 59
Contact email:
Contact Phone:
Randomized:
Randomized
IV or Oral:
Oral
Trial Notes:
A Prospective, Multicenter, Randomized, Open-Label, Active-Controlled, 2-Parallel Group, Phase III Study to Compare Efficacy and Safety of Masitinib at 7.5 mg/kg/Day to Imatinib at 400 or 600 mg in Treatment of Patients With Gastro-Intestinal Stromal Tumour in First Line Medical Treatment

Trial Links

 
 
 

Trial Results

Drug Information

AB Science website
 
Comparative Toxicogenomics Database
 
Masitinib as an adjunct therapy for mild-to-moderate Alzheimer's disease: a randomised, placebo-controlled phase 2 trial
 
Masitinib Phase II Trial Reports Benefit in New GISTs
 
Masitinib, (AB1010), a potent and selective TKI of targeting KIT (PDF)
 
Press Release - Masitinib extends overall survival in randomized phase II trial for GIST vs. Sutent for second line treatment
 
Oral tyrosine kinase inhibitor masitinib in combination with gemcitabine in patients with advanced pancreatic cancer: A multicenter phase II study.
 
AB Science reports phase 3 study results of masitinib in combination with Gemzar® for treatment of pancreatic cancer. Read more: AB Science reports phase 3 study results of masitinib in combination with Gemzar® for treatment of pancreatic cancer. - FiercePharma http://www.fiercepharma.com/press-releases/ab-science-reports-phase-3-study-results-masitinib-combination-gemzar-treat#ixzz2AsvsdSb7 Subscribe: http://www.fiercepharma.com/signup?sourceform=Viral-Tynt-FiercePharma-FiercePharma
 
AB Science announces a voluntary hold in the clinical studies of Masitinib worldwide (Jun, 2021).
 

Trial Sites

Name
Address
City
State
Zip
Country
Orlando
FL
32806
USA
Detroit
MI
48202
USA
New York
NY
10003
USA
Lille
Nord
59020
France
28 rue Laennec
Lyon
Rhone
69373
France
Dijon
France
Rouen
France
Dreux
France
Saint-Cloud
France
Nantes
France
Besancon
Doubs
25030
France
Marseilles
13273
France
Montpellier
France
Orleans
France
Paris
Ile de France
75908
France
229 Cours Argonne
Bordeaux
Gironde
33076
France
Reims
Marne
51092
France
Beirut
Lebanon
Dora
Lebanon
Bsalim
Lebanon
Saida
Lebanon
1365C Clifton Road
Atlanta
GA
30322
USA
300 W. 10th Ave.
Columbus
OH
43210
USA
Greenville
SC
29615
USA
8701 Watertown Plank Rd.
Milwaukee
WI
53226
USA
Abbeville
80142
France
Avignon
84000
France
Brest
29200
France
Creteil
94000
France
Evreux
27000
France
Gap
05000
France
La Roche sur Yon
85925
France
La Rochelle
17000
France
Libourne
33500
France
Paris
75018
France
Paris
75012
France
Paris
75020
France
Beirut
Lebanon
Beirut
Lebanon
Beirut
Lebanon
Dijon
21079
France
Saint Brieuc
22000
France
Wels
Austria
Wien
Austria
Salzburg
Austria
Salzburg
Austria
Rankweil
Austria
Edegem
Belgium
Brussels
Belgium
Angers
France
Bobigny
France
Caen
France
Clermont Ferrand
France
Grenoble
France
Mont de Marsan
France
Nice
France
Nimes
France
Paris
France
Paris
France
Paris
France
Paris
France
Paris
France
Paris
France
Paris
75571
France
Pau
France
Reimes
France
Saint Nazaire
France
Saint Priest en Jarez
France
Strasbourg
France
50937 Koln
GERMANY
55131 Mainz
GERMANY
81 675 Munchen
GERMANY
Nyiregyháza
Hungary
Pécs
Hungary
Szeged
Hungary
Zalaegerszeg
Hungary
Beirut
Lebanon
Metn
Lebanon
Spain
Tenerife
38320
Spain
Barcelona
Spain
Barcelona
08041
Spain
Barcelona
08035
Spain
Madrid
Spain
Madrid
Spain
Madrid
Spain
Madrid
Spain
Plamplona
Spain
Valencia
Spain
Bangkok
Thailand
Manchester
M20 4BX
UK
Strasbourg
67065
France
800 Prudential Dr
Jacksonville
FL
32207
USA
203 Cox Boulevard
Goldsboro
NC
27534
USA
801 Ostrum Street
Bethlehem
PA
18015
USA
1600 SW Archer Road
Gainesville
FL
32610-0277
USA
Los Angeles
CA
USA
Baltimore
MD
USA
Pittsburgh
PA
15232
USA
Dayton
OH
USA
1475 Northwest 12th Ave
Miami
FL
33136
USA