TRIAL DETAIL

An Open Label Treatment Extension Study of AMG 706

Drug:
Trial Name:
An Open Label Treatment Extension Study of AMG 706
NCT#:
Conditions:
Solid Tumors
Status:
Ongoing, but not recruiting
Phase:
2
Start Date 12/01/2005
Age of Trial (yrs) 18.4
Treatment Phase:
Extension Study
Drug Category:
KIT/PDGFRA inhibitor VEGFR inhibitor (TKI)
Strategy:
Block KIT
Trial Type:
GIST not specified. GIST patient enrollment unknown.
Other Protocol IDs:
20050130
Sponsor:
Amgen Inc.
Patient Contact:
Amgen Call Center
Contact email:
Contact Phone:
866-572-6436
Randomized:
IV or Oral:
Oral
Trial Notes:
This is an extension study to provide ongoing treatment with AMG 706 monotherapy for subjects with solid tumors who have completed the planned duration of treatment with AMG 706 on a previous/separate Amgen protocol and demonstrated continuing clinical benefit.

Trial Links

Trial Results

Drug Information

AMG 706 - Cancer Research - Full text
 
Motesanib in thyroid cancer - NEJM
 
The Molecular Basis of Class Side Effects Due to Treatment with Inhibitors of the VEGF/VEGFR Pathway
 
Amgen pipeline-Motesanib
 
Motesanib inhibits Kit mutations associated with gastrointestinal stromal tumors. (full text article)
 

Trial Sites

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