TRIAL DETAIL

L-carnitine vs Placebo for the Treatment of Muscle Cramps After Imatinib in Gastrointestinal Stromal Tumors

Drug:
Trial Name:
L-carnitine vs Placebo for the Treatment of Muscle Cramps After Imatinib in Gastrointestinal Stromal Tumors
NCT#:
Conditions:
Gastrointestinal Stromal Tumor
Status:
Completed
Phase:
3
Start Date 03/01/2018
Age of Trial (yrs) 6.7
Treatment Phase:
Management
Drug Category:
Strategy:
Trial Type:
Specifically GIST and only GIST
Other Protocol IDs:
AMC1801
Sponsor:
Asan Medical Center
Patient Contact:
Yoon-Koo Kang, MD, PhD +82-2-3010-3230 ykkang@amc.seoul.kr
Contact email:
Contact Phone:
Randomized:
Randomized
IV or Oral:
Oral
Trial Notes:
Detailed Description:

One of the most common side effects of imatinib treatment, muscle cramps occur in about 30% of patients with gastrointestinal stromal tumor (GIST) receiving treatment with imatinib.

It affects the quality of life (QoL) of patients and could also be a factor that affects compliance with treatment. Some studies suggest that L-carnitine may improve muscle cramps associated with cirrhosis or hemodialysis. However, the efficacy of L-carnitine for muscle cramps occurring after imatinib treatment has yet to be reported. Thus, we aim to evaluate the efficacy of L-carnitine for the treatment of muscle cramps after imatinib in patients with GIST and apply in the future.

Trial Links

Trial Results
 

Drug Information

Trial Sites

Name
Address
City
State
Zip
Country
Seoul
Songpa-gu
138-736
Republic of Korea