TRIAL DETAIL

Phase 1 dose-escalation study of oral tyrosine kinase inhibitor masitinib in advanced and/or metastatic solid cancers

Drug:
Trial Name:
Phase 1 dose-escalation study of oral tyrosine kinase inhibitor masitinib in advanced and/or metastatic solid cancers
NCT#:
Conditions:
Solid Tumors
Status:
Completed
Phase:
1
Start Date 01/01/2004
Age of Trial (yrs) 18.5
Treatment Phase:
Gleevec-resistant
Drug Category:
KIT/PDGFRA inhibitor
Strategy:
Block KIT
Trial Type:
GIST not specified. GIST patients known to be enrolled.
Other Protocol IDs:
Sponsor:
AB Science
Patient Contact:
Contact email:
Contact Phone:
Randomized:
IV or Oral:
Oral
Trial Notes:

Trial Links

Trial Results

 
 

Drug Information

AB Science website
 
Comparative Toxicogenomics Database
 
Masitinib as an adjunct therapy for mild-to-moderate Alzheimer's disease: a randomised, placebo-controlled phase 2 trial
 
Masitinib Phase II Trial Reports Benefit in New GISTs
 
Masitinib, (AB1010), a potent and selective TKI of targeting KIT (PDF)
 
Press Release - Masitinib extends overall survival in randomized phase II trial for GIST vs. Sutent for second line treatment
 
Oral tyrosine kinase inhibitor masitinib in combination with gemcitabine in patients with advanced pancreatic cancer: A multicenter phase II study.
 
AB Science reports phase 3 study results of masitinib in combination with Gemzar® for treatment of pancreatic cancer. Read more: AB Science reports phase 3 study results of masitinib in combination with Gemzar® for treatment of pancreatic cancer. - FiercePharma http://www.fiercepharma.com/press-releases/ab-science-reports-phase-3-study-results-masitinib-combination-gemzar-treat#ixzz2AsvsdSb7 Subscribe: http://www.fiercepharma.com/signup?sourceform=Viral-Tynt-FiercePharma-FiercePharma
 
AB Science announces a voluntary hold in the clinical studies of Masitinib worldwide (Jun, 2021).
 

Trial Sites

Name
Address
City
State
Zip
Country
Villejuif
Val de Narne
94805
France
28 rue Laennec
Lyon
Rhone
69373
France
229 Cours Argonne
Bordeaux
Gironde
33076
France