Drug: |
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Trial Name: |
Safety Study Of SNX-5422 To Treat Solid Tumor Cancers And Lymphomas |
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NCT#: |
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Conditions: |
Solid Tumors |
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Status: |
Completed |
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Phase: |
1 |
Start Date 03/01/2008 |
Age of Trial (yrs) 17.1 |
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Treatment Phase: |
Gleevec-resistant |
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Drug Category: |
HSP90 inhibitor |
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Strategy: |
Destroy KIT |
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Trial Type: |
GIST not specified. GIST patient enrollment unknown. |
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Other Protocol IDs: |
B1311003, PO7318 |
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Sponsor: |
Pfizer,
NCI |
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Patient Contact: |
Pfizer Oncology Clinical Trial Information Service
1-877-369-9753
PfizerCancerTrials@emergingmed.com
Pfizer CT.gov Call Center
1-800-718-1021 |
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Contact email: |
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Contact Phone: |
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Randomized: |
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IV or Oral: |
Oral |
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Trial Notes: |
SNX-5422 is an oral HSP90 inhibitor made by Seranex. This phase I trial allows patients with solid tumors or lymphomas. Phase I trials are designed to evaluate the safety of a drug and to establish safe/tolerable levels for later trials. The development of SNX-5422 has been discontinued because of ocular toxicity seen in animal models and in a phase I study. Clin Cancer Res; 17(21); 1–9. ©2011 AACR. |
Trial Links |
Trial Results |
Drug Information |
Name |
Address |
City |
State |
Zip |
Country |
Bethesda |
MD |
20982 |
USA |