TRIAL DETAIL

Safety Study Of SNX-5422 To Treat Solid Tumor Cancers And Lymphomas

Drug:
Trial Name:
Safety Study Of SNX-5422 To Treat Solid Tumor Cancers And Lymphomas
NCT#:
Conditions:
Solid Tumors
Status:
Completed
Phase:
1
Start Date 03/01/2008
Age of Trial (yrs) 16.2
Treatment Phase:
Gleevec-resistant
Drug Category:
HSP90 inhibitor
Strategy:
Destroy KIT
Trial Type:
GIST not specified. GIST patient enrollment unknown.
Other Protocol IDs:
B1311003, PO7318
Sponsor:
Pfizer, NCI
Patient Contact:
Pfizer Oncology Clinical Trial Information Service 1-877-369-9753 PfizerCancerTrials@emergingmed.com Pfizer CT.gov Call Center 1-800-718-1021
Contact email:
Contact Phone:
Randomized:
IV or Oral:
Oral
Trial Notes:
SNX-5422 is an oral HSP90 inhibitor made by Seranex. This phase I trial allows patients with solid tumors or lymphomas.
Phase I trials are designed to evaluate the safety of a drug and to establish safe/tolerable levels for later trials.
The development of SNX-5422 has been discontinued because of ocular toxicity seen in animal models and in a phase I study. Clin Cancer Res; 17(21); 1–9. ©2011 AACR.

Trial Links

Trial Results

Drug Information

Trial Sites

Name
Address
City
State
Zip
Country
Bethesda
MD
20982
USA